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LEO1 LEO1 homolog, Paf1/RNA polymerase II complex component [ Canis lupus familiaris (dog) ]

Gene ID: 478310, updated on 27-Jun-2026
Official Symbol
LEO1provided by VGNC
Official Full Name
LEO1 homolog, Paf1/RNA polymerase II complex componentprovided by VGNC
Primary source
VGNC:VGNC:59117
See related
Ensembl:ENSCAFG00845026719 RGD:12266744
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
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See LEO1 in Genome Data Viewer
Location:
chromosome: 30
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (17760917..17798265, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (17541113..17578528, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (17906850..17943999, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (17682358..17719762, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (17800296..17837557, complement)

Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene tropomodulin 3 Neighboring gene V-type proton ATPase subunit E 1-like Neighboring gene uncharacterized LOC119866893 Neighboring gene RNA polymerase-associated protein LEO1-like Neighboring gene natural cytotoxicity triggering receptor 3 ligand 1-like Neighboring gene uncharacterized LOC111093291

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II C-terminal domain phosphoserine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription elongation by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transcription elongation by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Cdc73/Paf1 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
RNA polymerase-associated protein LEO1
Names
Leo1, Paf1/RNA polymerase II complex component, homolog

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051834.1 Reference ROS_Cfam_1.0

    Range
    17760917..17798265 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038442346.1 → XP_038298274.1  RNA polymerase-associated protein LEO1

    UniProtKB/TrEMBL
    A0A8C0L2V1, A0A8I3PZ91, A0A8I3PZU5
    Related
    ENSCAFP00845037112.1, ENSCAFT00845047288.1
    Conserved Domains (2) summary
    pfam04004
    Location:373 → 535
    Leo1; Leo1-like protein
    NF033609
    Location:9 → 360
    MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049290.1 Alternate UMICH_Zoey_3.1

    Range
    17682358..17719762 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038516795.1 → XP_038372723.1  

    Conserved Domains (2) summary
    pfam04004
    Location:373 → 535
    Leo1; Leo1-like protein
    NF033609
    Location:9 → 360
    MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

    Range
    17800296..17837557 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038644731.1 → XP_038500659.1  

    Conserved Domains (2) summary
    pfam04004
    Location:373 → 535
    Leo1; Leo1-like protein
    NF033609
    Location:9 → 360
    MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

    Range
    17906850..17943999 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038580433.1 → XP_038436361.1  RNA polymerase-associated protein LEO1

    UniProtKB/TrEMBL
    A0A8C0L2V1, A0A8I3PZ91, A0A8I3PZU5
    Conserved Domains (2) summary
    pfam04004
    Location:373 → 535
    Leo1; Leo1-like protein
    NF033609
    Location:9 → 360
    MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    17541113..17578528 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_535485.7 → XP_535485.2  RNA polymerase-associated protein LEO1

    UniProtKB/TrEMBL
    A0A8C0L2V1, A0A8I3PZ91, A0A8I3PZU5
    Conserved Domains (2) summary
    pfam04004
    Location:373 → 535
    Leo1; Leo1-like protein
    NF033609
    Location:9 → 360
    MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA
Nucleotide Protein
Heading Accession and Version

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