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PLK2 polo like kinase 2 [ Canis lupus familiaris (dog) ]

Gene ID: 478063, updated on 27-Jun-2026
Official Symbol
PLK2provided by VGNC
Official Full Name
polo like kinase 2provided by VGNC
Primary source
VGNC:VGNC:44696
See related
Ensembl:ENSCAFG00845029116 RGD:12393367
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See PLK2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (45844932..45850642, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (42431127..42436818, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (44541169..44546873, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (42914745..42920462, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (43720594..43726300, complement)

Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119870006 Neighboring gene uncharacterized LOC111094652 Neighboring gene GRB2 binding adaptor protein, transmembrane Neighboring gene RAB3C, member RAS oncogene family Neighboring gene uncharacterized LOC111092291

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
serine/threonine-protein kinase PLK2
XP_038325762.1
XP_038386570.1
XP_038450816.1
XP_038514863.1
XP_535242.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051806.1 Reference ROS_Cfam_1.0

    Range
    45844932..45850642 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038658935.1 → XP_038514863.1  serine/threonine-protein kinase PLK2

    UniProtKB/TrEMBL
    A0A8C0LJ77, A0A8I3Q2H2, A0A8I3Q7E3
    Related
    ENSCAFP00845040473.1, ENSCAFT00845051580.1
    Conserved Domains (3) summary
    cd13117
    Location:602 → 683
    POLO_box_2; Second polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
    cd13118
    Location:504 → 589
    POLO_box_1; First polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
    cd14188
    Location:81 → 335
    STKc_PLK2; Catalytic domain of the Serine/Threonine Kinase, Polo-like kinase 2

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049262.1 Alternate UMICH_Zoey_3.1

    Range
    42914745..42920462 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038469834.1 → XP_038325762.1  

    Conserved Domains (3) summary
    cd13117
    Location:602 → 683
    POLO_box_2; Second polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
    cd13118
    Location:504 → 589
    POLO_box_1; First polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
    cd14188
    Location:81 → 335
    STKc_PLK2; Catalytic domain of the Serine/Threonine Kinase, Polo-like kinase 2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

    Range
    43720594..43726300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038594888.1 → XP_038450816.1  

    Conserved Domains (3) summary
    cd13117
    Location:602 → 683
    POLO_box_2; Second polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
    cd13118
    Location:504 → 589
    POLO_box_1; First polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
    cd14188
    Location:81 → 335
    STKc_PLK2; Catalytic domain of the Serine/Threonine Kinase, Polo-like kinase 2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

    Range
    44541169..44546873 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038530642.1 → XP_038386570.1  serine/threonine-protein kinase PLK2

    UniProtKB/TrEMBL
    A0A8C0LJ77, A0A8I3Q2H2, A0A8I3Q7E3
    Conserved Domains (3) summary
    cd13117
    Location:602 → 683
    POLO_box_2; Second polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
    cd13118
    Location:504 → 589
    POLO_box_1; First polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
    cd14188
    Location:81 → 335
    STKc_PLK2; Catalytic domain of the Serine/Threonine Kinase, Polo-like kinase 2

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    42431127..42436818 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_535242.8 → XP_535242.1  serine/threonine-protein kinase PLK2

    UniProtKB/TrEMBL
    A0A8I3Q2H2
    Conserved Domains (4) summary
    smart00220
    Location:83 → 335
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd13117
    Location:602 → 683
    POLO_box_2; Second polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
    cd13118
    Location:504 → 589
    POLO_box_1; First polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5
    cd14188
    Location:81 → 335
    STKc_PLK2; Catalytic domain of the Serine/Threonine Kinase, Polo-like kinase 2
Nucleotide Protein
Heading Accession and Version

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