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NT5C2 5'-nucleotidase, cytosolic II [ Canis lupus familiaris (dog) ]

Gene ID: 477809, updated on 25-Jul-2026
Official Symbol
NT5C2provided by VGNC
Official Full Name
5'-nucleotidase, cytosolic IIprovided by VGNC
Primary source
VGNC:VGNC:43996
See related
Ensembl:ENSCAFG00845026627 RGD:12428381
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See NT5C2 in Genome Data Viewer
Location:
chromosome: 28
Exon count:
25
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 28 NC_051832.1 (16000755..16095008, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 28 NC_006610.4 (15697211..15791400, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 28 NC_049249.1 (15716631..15810917, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 28 NC_049288.1 (15550611..15644750, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 28 NC_049769.1 (15581995..15676317, complement)

Chromosome 28 - NC_051832.1Genomic Context describing neighboring genes Neighboring gene arsenite methyltransferase Neighboring gene cyclin and CBS domain divalent metal cation transport mediator 2 Neighboring gene activated RNA polymerase II transcriptional coactivator p15-like Neighboring gene 60S ribosomal protein L23a-like Neighboring gene nucleoside diphosphate kinase, mitochondrial-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-nucleotidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in IMP metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adenosine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
cytosolic purine 5'-nucleotidase
XP_005637739.1
XP_005637740.1
XP_005637741.1
XP_005637742.1
XP_005637743.1
XP_022267685.1
XP_038296369.1
XP_038296370.1
XP_038296371.1
XP_038296372.1
XP_038296373.1
XP_038296374.1
XP_038296375.1
XP_038296376.1
XP_038296377.1
XP_038316675.1
XP_038370991.1
XP_038370992.1
XP_038370993.1
XP_038370994.1
XP_038370995.1
XP_038370996.1
XP_038370997.1
XP_038370998.1
XP_038370999.1
XP_038434595.1
XP_038434596.1
XP_038434597.1
XP_038434598.1
XP_038434599.1
XP_038434600.1
XP_038434601.1
XP_038434602.1
XP_038434603.1
XP_038498779.1
XP_038498780.1
XP_038498781.1
XP_038498782.1
XP_038498783.1
XP_038498784.1
XP_038498785.1
XP_038498786.1
XP_038498787.1
XP_535002.2
XP_863659.2

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051832.1 Reference ROS_Cfam_1.0

    Range
    16000755..16095008 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038440444.1 → XP_038296372.1  cytosolic purine 5'-nucleotidase isoform X2

    UniProtKB/TrEMBL
    A0A8C0KC57, A0A8I3PWT8
    Related
    ENSCAFP00845036838.1, ENSCAFT00845046956.1
    Conserved Domains (1) summary
    pfam05761
    Location:43 → 488
    5_nucleotid; 5' nucleotidase family

  2. XM_038440441.1 → XP_038296369.1  cytosolic purine 5'-nucleotidase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KC57, A0A8I3QC03
    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  3. XM_038440443.1 → XP_038296371.1  cytosolic purine 5'-nucleotidase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KC57, A0A8I3QC03
    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  4. XM_038440442.1 → XP_038296370.1  cytosolic purine 5'-nucleotidase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KC57, A0A8I3QC03
    Related
    ENSCAFP00845036998.1, ENSCAFT00845047148.1
    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  5. XM_038440445.1 → XP_038296373.1  cytosolic purine 5'-nucleotidase isoform X3

    UniProtKB/TrEMBL
    A0A8C0KC57
    Related
    ENSCAFP00845036931.1, ENSCAFT00845047059.1
    Conserved Domains (1) summary
    pfam05761
    Location:14 → 467
    5_nucleotid; 5' nucleotidase family

  6. XM_038440447.1 → XP_038296375.1  cytosolic purine 5'-nucleotidase isoform X5

    UniProtKB/TrEMBL
    A0A8C0KC57
    Conserved Domains (1) summary
    pfam05761
    Location:11 → 456
    5_nucleotid; 5' nucleotidase family

  7. XM_038440446.1 → XP_038296374.1  cytosolic purine 5'-nucleotidase isoform X4

    UniProtKB/TrEMBL
    A0A8C0KC57
    Conserved Domains (1) summary
    pfam05761
    Location:11 → 464
    5_nucleotid; 5' nucleotidase family

  8. XM_038440449.1 → XP_038296377.1  cytosolic purine 5'-nucleotidase isoform X6

    UniProtKB/TrEMBL
    A0A8I3QF96
    Conserved Domains (1) summary
    cl17687
    Location:1 → 297
    5_nucleotid; 5' nucleotidase family

  9. XM_038440448.1 → XP_038296376.1  cytosolic purine 5'-nucleotidase isoform X6

    UniProtKB/TrEMBL
    A0A8I3QF96
    Conserved Domains (1) summary
    cl17687
    Location:1 → 297
    5_nucleotid; 5' nucleotidase family

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049288.1 Alternate UMICH_Zoey_3.1

    Range
    15550611..15644750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038515066.1 → XP_038370994.1  

    Conserved Domains (1) summary
    pfam05761
    Location:43 → 488
    5_nucleotid; 5' nucleotidase family

  2. XM_038515063.1 → XP_038370991.1  

    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  3. XM_038515065.1 → XP_038370993.1  

    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  4. XM_038515064.1 → XP_038370992.1  

    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  5. XM_038515067.1 → XP_038370995.1  

    Conserved Domains (1) summary
    pfam05761
    Location:14 → 467
    5_nucleotid; 5' nucleotidase family

  6. XM_038515069.1 → XP_038370997.1  

    Conserved Domains (1) summary
    pfam05761
    Location:11 → 456
    5_nucleotid; 5' nucleotidase family

  7. XM_038515068.1 → XP_038370996.1  

    Conserved Domains (1) summary
    pfam05761
    Location:11 → 464
    5_nucleotid; 5' nucleotidase family

  8. XM_038515071.1 → XP_038370999.1  

    Conserved Domains (1) summary
    cl17687
    Location:1 → 297
    5_nucleotid; 5' nucleotidase family

  9. XM_038515070.1 → XP_038370998.1  

    Conserved Domains (1) summary
    cl17687
    Location:1 → 297
    5_nucleotid; 5' nucleotidase family

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049769.1 Alternate UNSW_CanFamBas_1.0

    Range
    15581995..15676317 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038642854.1 → XP_038498782.1  

    Conserved Domains (1) summary
    pfam05761
    Location:43 → 488
    5_nucleotid; 5' nucleotidase family

  2. XM_038642851.1 → XP_038498779.1  

    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  3. XM_038642853.1 → XP_038498781.1  

    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  4. XM_038642852.1 → XP_038498780.1  

    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  5. XM_038642855.1 → XP_038498783.1  

    Conserved Domains (1) summary
    pfam05761
    Location:14 → 467
    5_nucleotid; 5' nucleotidase family

  6. XM_038642857.1 → XP_038498785.1  

    Conserved Domains (1) summary
    pfam05761
    Location:11 → 456
    5_nucleotid; 5' nucleotidase family

  7. XM_038642856.1 → XP_038498784.1  

    Conserved Domains (1) summary
    pfam05761
    Location:11 → 464
    5_nucleotid; 5' nucleotidase family

  8. XM_038642859.1 → XP_038498787.1  

    Conserved Domains (1) summary
    cl17687
    Location:1 → 297
    5_nucleotid; 5' nucleotidase family

  9. XM_038642858.1 → XP_038498786.1  

    Conserved Domains (1) summary
    cl17687
    Location:1 → 297
    5_nucleotid; 5' nucleotidase family

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049249.1 Alternate UU_Cfam_GSD_1.0

    Range
    15716631..15810917 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038578670.1 → XP_038434598.1  cytosolic purine 5'-nucleotidase isoform X2

    UniProtKB/TrEMBL
    A0A8C0KC57, A0A8I3PWT8
    Conserved Domains (1) summary
    pfam05761
    Location:43 → 488
    5_nucleotid; 5' nucleotidase family

  2. XM_038578667.1 → XP_038434595.1  cytosolic purine 5'-nucleotidase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KC57, A0A8I3QC03
    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  3. XM_038578669.1 → XP_038434597.1  cytosolic purine 5'-nucleotidase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KC57, A0A8I3QC03
    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  4. XM_038578668.1 → XP_038434596.1  cytosolic purine 5'-nucleotidase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KC57, A0A8I3QC03
    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  5. XM_038578671.1 → XP_038434599.1  cytosolic purine 5'-nucleotidase isoform X3

    UniProtKB/TrEMBL
    A0A8C0KC57
    Conserved Domains (1) summary
    pfam05761
    Location:14 → 467
    5_nucleotid; 5' nucleotidase family

  6. XM_038578673.1 → XP_038434601.1  cytosolic purine 5'-nucleotidase isoform X5

    UniProtKB/TrEMBL
    A0A8C0KC57
    Conserved Domains (1) summary
    pfam05761
    Location:11 → 456
    5_nucleotid; 5' nucleotidase family

  7. XM_038578672.1 → XP_038434600.1  cytosolic purine 5'-nucleotidase isoform X4

    UniProtKB/TrEMBL
    A0A8C0KC57
    Conserved Domains (1) summary
    pfam05761
    Location:11 → 464
    5_nucleotid; 5' nucleotidase family

  8. XM_038578675.1 → XP_038434603.1  cytosolic purine 5'-nucleotidase isoform X6

    UniProtKB/TrEMBL
    A0A8I3QF96
    Conserved Domains (1) summary
    cl17687
    Location:1 → 297
    5_nucleotid; 5' nucleotidase family

  9. XM_038578674.1 → XP_038434602.1  cytosolic purine 5'-nucleotidase isoform X6

    UniProtKB/TrEMBL
    A0A8I3QF96
    Conserved Domains (1) summary
    cl17687
    Location:1 → 297
    5_nucleotid; 5' nucleotidase family

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006610.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    15697211..15791400 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_535002.7 → XP_535002.2  cytosolic purine 5'-nucleotidase isoform X2

    UniProtKB/TrEMBL
    A0A8C0KC57, A0A8I3PWT8
    Conserved Domains (1) summary
    pfam05761
    Location:43 → 488
    5_nucleotid; 5' nucleotidase family

  2. XM_005637682.4 → XP_005637739.1  cytosolic purine 5'-nucleotidase isoform X1

    See identical proteins and their annotated locations for XP_005637739.1

    UniProtKB/TrEMBL
    A0A8C0KC57, A0A8I3QC03
    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  3. XM_005637683.4 → XP_005637740.1  cytosolic purine 5'-nucleotidase isoform X1

    See identical proteins and their annotated locations for XP_005637740.1

    UniProtKB/TrEMBL
    A0A8C0KC57, A0A8I3QC03
    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  4. XM_005637684.4 → XP_005637741.1  cytosolic purine 5'-nucleotidase isoform X1

    See identical proteins and their annotated locations for XP_005637741.1

    UniProtKB/TrEMBL
    A0A8C0KC57, A0A8I3QC03
    Conserved Domains (1) summary
    pfam05761
    Location:43 → 496
    5_nucleotid; 5' nucleotidase family

  5. XM_858566.6 → XP_863659.2  cytosolic purine 5'-nucleotidase isoform X3

    UniProtKB/TrEMBL
    A0A8C0KC57
    Conserved Domains (1) summary
    pfam05761
    Location:14 → 467
    5_nucleotid; 5' nucleotidase family

  6. XM_005637686.4 → XP_005637743.1  cytosolic purine 5'-nucleotidase isoform X5

    UniProtKB/TrEMBL
    A0A8C0KC57
    Conserved Domains (1) summary
    pfam05761
    Location:11 → 456
    5_nucleotid; 5' nucleotidase family

  7. XM_005637685.4 → XP_005637742.1  cytosolic purine 5'-nucleotidase isoform X4

    UniProtKB/TrEMBL
    A0A8C0KC57
    Conserved Domains (1) summary
    pfam05761
    Location:11 → 464
    5_nucleotid; 5' nucleotidase family

  8. XM_038460747.1 → XP_038316675.1  cytosolic purine 5'-nucleotidase isoform X6

    UniProtKB/TrEMBL
    A0A8I3QF96
    Conserved Domains (1) summary
    cl17687
    Location:1 → 297
    5_nucleotid; 5' nucleotidase family

  9. XM_022411977.1 → XP_022267685.1  cytosolic purine 5'-nucleotidase isoform X6

    UniProtKB/TrEMBL
    A0A8I3QF96
    Conserved Domains (1) summary
    cl17687
    Location:1 → 297
    5_nucleotid; 5' nucleotidase family
Nucleotide Protein
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