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HTR7 5-hydroxytryptamine receptor 7 [ Canis lupus familiaris (dog) ]

Gene ID: 477762, updated on 5-Mar-2024

Summary

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Official Symbol
HTR7provided by VGNC
Official Full Name
5-hydroxytryptamine receptor 7provided by VGNC
Primary source
VGNC:VGNC:41834
See related
Ensembl:ENSCAFG00845029113
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See HTR7 in Genome Data Viewer
Location:
chromosome: 28
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 28 NC_051832.1 (5658606..5744502, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 28 NC_006610.4 (5605815..5691701, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 28 NC_049249.1 (5588358..5595285, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 28 NC_049288.1 (5415879..5501608, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 28 NC_049769.1 (5454660..5540434, complement)

Chromosome 28 - NC_051832.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102152390 Neighboring gene uncharacterized LOC111093015 Neighboring gene ribonuclease P/MRP subunit p30 Neighboring gene ankyrin repeat domain 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of 5-HT7-receptor-mediated gastric relaxation in conscious dogs. Janssen P, et al. Am J Physiol Gastrointest Liver Physiol, 2005 Jul. PMID 15746214
  2. 5-HT7 receptor efficacy distribution throughout the canine stomach. Janssen P, et al. Br J Pharmacol, 2004 Oct. PMID 15339857, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Proximal stomach relaxation in conscious dogs before and after vagotomy is mediated via 5-HT(7) receptor.
    Title: Characterization of 5-HT7-receptor-mediated gastric relaxation in conscious dogs.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled serotonin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in circadian rhythm IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in smooth muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vasoconstriction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5-hydroxytryptamine receptor 7
Names
5-HT receptor 7a
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051832.1 Reference ROS_Cfam_1.0

    Range
    5658606..5744502 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038439912.1 → XP_038295840.1  5-hydroxytryptamine receptor 7 isoform X1

    UniProtKB/TrEMBL
    Q684P8
    Related
    ENSCAFP00845040436.1, ENSCAFT00845051533.1
    Conserved Domains (1) summary
    cd15329
    Location:84 → 398
    7tmA_5-HT7; serotonin receptor subtype 7, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038439914.1 → XP_038295842.1  5-hydroxytryptamine receptor 7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NZQ1, A0A8C0TTM4, A0A8I3S709
    Related
    ENSCAFP00845040423.1, ENSCAFT00845051517.1
    Conserved Domains (1) summary
    cd15329
    Location:84 → 398
    7tmA_5-HT7; serotonin receptor subtype 7, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049288.1 Alternate UMICH_Zoey_3.1

    Range
    5415879..5501608 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038514525.1 → XP_038370453.1  5-hydroxytryptamine receptor 7 isoform X1

  2. XM_038514526.1 → XP_038370454.1  5-hydroxytryptamine receptor 7 isoform X2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049769.1 Alternate UNSW_CanFamBas_1.0

    Range
    5454660..5540434 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038642339.1 → XP_038498267.1  5-hydroxytryptamine receptor 7 isoform X1

  2. XM_038642340.1 → XP_038498268.1  5-hydroxytryptamine receptor 7 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049249.1 Alternate UU_Cfam_GSD_1.0

    Range
    5588358..5595285 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038577939.1 → XP_038433867.1  5-hydroxytryptamine receptor 7 isoform X3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006610.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    5605815..5691701 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_534958.7 → XP_534958.2  5-hydroxytryptamine receptor 7 isoform X1

    UniProtKB/TrEMBL
    Q684P8
    Conserved Domains (1) summary
    cd15329
    Location:84 → 398
    7tmA_5-HT7; serotonin receptor subtype 7, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_005637529.4 → XP_005637586.1  5-hydroxytryptamine receptor 7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NZQ1, A0A8C0TTM4, A0A8I3S709
    Conserved Domains (1) summary
    cd15329
    Location:84 → 398
    7tmA_5-HT7; serotonin receptor subtype 7, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein
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