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LOC477699 alpha-2-macroglobulin [ Canis lupus familiaris (dog) ]

Gene ID: 477699, updated on 10-Sep-2017
Gene symbol
LOC477699
Gene description
alpha-2-macroglobulin
See related
Ensembl:ENSCAFG00000025567
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
A2M
See LOC477699 in Genome Data Viewer
Location:
chromosome: 27
Exon count:
36
Annotation release Status Assembly Chr Location
105 current CanFam3.1 (GCF_000002285.3) 27 NC_006609.3 (36654328..36695775)

Chromosome 27 - NC_006609.3Genomic Context describing neighboring genes Neighboring gene pregnancy zone protein-like Neighboring gene ORM1-like protein 2 pseudogene Neighboring gene pregnancy-zone protein Neighboring gene killer cell lectin like receptor G1 Neighboring gene mannose-6-phosphate receptor, cation dependent

Genomic Sequence:
NC_006609.3 Chromosome 27 Reference CanFam3.1 Primary Assembly

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Homology

Preferred Names
alpha-2-macroglobulin-P; alpha-2-macroglobulin

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006609.3 Reference CanFam3.1 Primary Assembly

    Range
    36654328..36695775
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_534893.6XP_534893.3  alpha-2-macroglobulin

    UniProtKB/TrEMBL
    F6UME0
    Related
    ENSCAFP00000020293.3, ENSCAFT00000021846.3
    Conserved Domains (7) summary
    COG2373
    Location:1241072
    YfaS; Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family [General function prediction only]
    cd02897
    Location:9591265
    A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...
    pfam00207
    Location:741831
    A2M; Alpha-2-macroglobulin family
    pfam01835
    Location:129221
    A2M_N; MG2 domain
    pfam07677
    Location:13771464
    A2M_recep; A-macroglobulin receptor
    pfam07678
    Location:10111267
    A2M_comp; A-macroglobulin complement component
    pfam07703
    Location:461606
    A2M_N_2; Alpha-2-macroglobulin family N-terminal region
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