U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OAS3 2'-5'-oligoadenylate synthetase 3 [ Canis lupus familiaris (dog) ]

Gene ID: 477490, updated on 25-Jul-2026
Official Symbol
OAS3provided by VGNC
Official Full Name
2'-5'-oligoadenylate synthetase 3provided by VGNC
Primary source
VGNC:VGNC:44088
See related
Ensembl:ENSCAFG00845022113 RGD:12402308
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See OAS3 in Genome Data Viewer
Location:
chromosome: 26
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 26 NC_051830.1 (10643960..10662689)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 26 NC_006608.4 (10522153..10540643)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 26 NC_049247.1 (10729355..10747851)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 26 NC_049286.1 (10617704..10636208)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 26 NC_049767.1 (10680918..10699398)

Chromosome 26 - NC_051830.1Genomic Context describing neighboring genes Neighboring gene rabphilin 3A Neighboring gene uncharacterized LOC119866154 Neighboring gene 2'-5'-oligoadenylate synthetase 1 Neighboring gene uncharacterized LOC119866156 Neighboring gene 2'-5'-oligoadenylate synthetase 2 Neighboring gene uncharacterized LOC111092704 Neighboring gene deltex E3 ubiquitin ligase 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The mammalian 2'-5' oligoadenylate synthetase gene family: evidence for concerted evolution of paralogous Oas1 genes in Rodentia and Artiodactyla. Perelygin AA, et al. J Mol Evol, 2006 Oct. PMID 17024523
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2'-5'-oligoadenylate synthetase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of viral genome replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of ribonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
2'-5'-oligoadenylate synthase 3
Names
2'-5'oligoadenylate synthetase 3
NP_001041556.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001048091.1 → NP_001041556.1  2'-5'-oligoadenylate synthase 3

    See identical proteins and their annotated locations for NP_001041556.1

    Status: PROVISIONAL

    Source sequence(s)
    AY916055
    UniProtKB/TrEMBL
    A0A8C0KW99, A0A8I3S2W7, Q2KKD1
    Related
    ENSCAFP00845030569.1, ENSCAFT00845039026.1
    Conserved Domains (2) summary
    cd05400
    Location:769 → 948
    NT_2-5OAS_ClassI-CCAase; Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme
    pfam10421
    Location:904 → 1086
    OAS1_C; 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051830.1 Reference ROS_Cfam_1.0

    Range
    10643960..10662689
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049286.1 Alternate UMICH_Zoey_3.1

    Range
    10617704..10636208
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049767.1 Alternate UNSW_CanFamBas_1.0

    Range
    10680918..10699398
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049247.1 Alternate UU_Cfam_GSD_1.0

    Range
    10729355..10747851
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006608.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    10522153..10540643
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials