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CASS4 Cas scaffold protein family member 4 [ Canis lupus familiaris (dog) ]

Gene ID: 477269, updated on 25-Jul-2026
Official Symbol
CASS4provided by VGNC
Official Full Name
Cas scaffold protein family member 4provided by VGNC
Primary source
VGNC:VGNC:38741
See related
RGD:12212705
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See CASS4 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (42332772..42368262)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (40869541..40905385)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (42369588..42405636)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (41572557..41608151)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (41711613..41747445)

Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene mitochondrial inner membrane scaffold 2 Neighboring gene aurora kinase A Neighboring gene cleavage stimulation factor subunit 1 Neighboring gene replication termination factor 2-like Neighboring gene cas scaffolding protein family member 4-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
cas scaffolding protein family member 4
Names
Cas scaffolding protein family member 4

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051828.1 Reference ROS_Cfam_1.0

    Range
    42332772..42368262
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038434139.1 → XP_038290067.1  cas scaffolding protein family member 4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q0F9
    Conserved Domains (4) summary
    PTZ00449
    Location:72 → 403
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd11568
    Location:656 → 777
    FAT-like_CASS4_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
    cd12000
    Location:14 → 70
    SH3_CASS4; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4
    pfam08824
    Location:434 → 589
    Serine_rich; Serine rich protein interaction domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049284.1 Alternate UMICH_Zoey_3.1

    Range
    41572557..41608151
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038509307.1 → XP_038365235.1  

    Conserved Domains (4) summary
    PTZ00449
    Location:72 → 369
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd11568
    Location:654 → 775
    FAT-like_CASS4_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
    cd12000
    Location:14 → 70
    SH3_CASS4; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4
    pfam08824
    Location:400 → 555
    Serine_rich; Serine rich protein interaction domain

  2. XM_038509306.1 → XP_038365234.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

    Range
    41711613..41747445
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038636920.1 → XP_038492848.1  

    Conserved Domains (4) summary
    PTZ00449
    Location:72 → 369
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd11568
    Location:654 → 775
    FAT-like_CASS4_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
    cd12000
    Location:14 → 70
    SH3_CASS4; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4
    pfam08824
    Location:400 → 555
    Serine_rich; Serine rich protein interaction domain

  2. XM_038636919.1 → XP_038492847.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

    Range
    42369588..42405636
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038572646.1 → XP_038428574.1  cas scaffolding protein family member 4 isoform X7

    UniProtKB/TrEMBL
    A0A8I3Q0F9

  2. XM_038572645.1 → XP_038428573.1  cas scaffolding protein family member 4 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q0F9

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    40869541..40905385
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038458099.1 → XP_038314027.1  cas scaffolding protein family member 4 isoform X9

    UniProtKB/TrEMBL
    A0A8I3Q0F9
    Conserved Domains (3) summary
    cd11568
    Location:654 → 775
    FAT-like_CASS4_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
    cd12000
    Location:14 → 70
    SH3_CASS4; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4
    pfam08824
    Location:400 → 555
    Serine_rich; Serine rich protein interaction domain

  2. XM_014107322.3 → XP_013962797.2  cas scaffolding protein family member 4 isoform X8

    UniProtKB/TrEMBL
    A0A8I3Q0F9
    Conserved Domains (4) summary
    PTZ00449
    Location:72 → 403
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cd11568
    Location:688 → 809
    FAT-like_CASS4_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
    cd12000
    Location:14 → 70
    SH3_CASS4; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4
    pfam08824
    Location:434 → 589
    Serine_rich; Serine rich protein interaction domain
Nucleotide Protein
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