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RARB retinoic acid receptor beta [ Canis lupus familiaris (dog) ]

Gene ID: 477045, updated on 17-Aug-2024

Summary

Official Symbol
RARBprovided by VGNC
Official Full Name
retinoic acid receptor betaprovided by VGNC
Primary source
VGNC:VGNC:45352
See related
Ensembl:ENSCAFG00845019290
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 23
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 23 NC_051827.1 (18509719..19020664, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 23 NC_006605.4 (18204235..18714201, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 23 NC_049244.1 (18545126..19056015, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 23 NC_049283.1 (18328357..18839472, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 23 NC_049764.1 (18431214..18948405, complement)

Chromosome 23 - NC_051827.1Genomic Context describing neighboring genes Neighboring gene N-glycanase 1 Neighboring gene 3-oxoacyl-ACP synthase, mitochondrial Neighboring gene DNA topoisomerase II beta Neighboring gene uncharacterized LOC111091903 Neighboring gene uncharacterized LOC119865367 Neighboring gene uncharacterized LOC119865368 Neighboring gene thyroid hormone receptor beta

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables nuclear glucocorticoid receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
retinoic acid receptor beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051827.1 Reference ROS_Cfam_1.0

    Range
    18509719..19020664 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038432140.1XP_038288068.1  retinoic acid receptor beta isoform X1

    Conserved Domains (2) summary
    cd06937
    Location:186416
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cd06964
    Location:82166
    NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
  2. XM_038432144.1XP_038288072.1  retinoic acid receptor beta isoform X4

    Conserved Domains (2) summary
    cd06937
    Location:67297
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:147
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
  3. XM_038432141.1XP_038288069.1  retinoic acid receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A8C0PKW1, A0A8C0R7A9, A0A8I3PGE5
    Related
    ENSCAFP00845026634.1, ENSCAFT00845034031.1
    Conserved Domains (2) summary
    cd06937
    Location:179409
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cd06964
    Location:75159
    NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
  4. XM_038432143.1XP_038288071.1  retinoic acid receptor beta isoform X4

    Conserved Domains (2) summary
    cd06937
    Location:67297
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:147
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
  5. XM_038432142.1XP_038288070.1  retinoic acid receptor beta isoform X3

    Conserved Domains (2) summary
    cd06937
    Location:81311
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:561
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049283.1 Alternate UMICH_Zoey_3.1

    Range
    18328357..18839472 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038507441.1XP_038363369.1  retinoic acid receptor beta isoform X1

    Conserved Domains (2) summary
    cd06937
    Location:186416
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cd06964
    Location:82166
    NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
  2. XM_038507445.1XP_038363373.1  retinoic acid receptor beta isoform X4

    Conserved Domains (2) summary
    cd06937
    Location:67297
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:147
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
  3. XM_038507442.1XP_038363370.1  retinoic acid receptor beta isoform X2

    Conserved Domains (2) summary
    cd06937
    Location:179409
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cd06964
    Location:75159
    NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
  4. XM_038507444.1XP_038363372.1  retinoic acid receptor beta isoform X4

    Conserved Domains (2) summary
    cd06937
    Location:67297
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:147
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
  5. XM_038507443.1XP_038363371.1  retinoic acid receptor beta isoform X3

    Conserved Domains (2) summary
    cd06937
    Location:81311
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:561
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049764.1 Alternate UNSW_CanFamBas_1.0

    Range
    18431214..18948405 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038634868.1XP_038490796.1  retinoic acid receptor beta isoform X1

    Conserved Domains (2) summary
    cd06937
    Location:186416
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cd06964
    Location:82166
    NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
  2. XM_038634872.1XP_038490800.1  retinoic acid receptor beta isoform X4

    Conserved Domains (2) summary
    cd06937
    Location:67297
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:147
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
  3. XM_038634869.1XP_038490797.1  retinoic acid receptor beta isoform X2

    Conserved Domains (2) summary
    cd06937
    Location:179409
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cd06964
    Location:75159
    NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
  4. XM_038634871.1XP_038490799.1  retinoic acid receptor beta isoform X4

    Conserved Domains (2) summary
    cd06937
    Location:67297
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:147
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
  5. XM_038634870.1XP_038490798.1  retinoic acid receptor beta isoform X3

    Conserved Domains (2) summary
    cd06937
    Location:81311
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:561
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049244.1 Alternate UU_Cfam_GSD_1.0

    Range
    18545126..19056015 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038570687.1XP_038426615.1  retinoic acid receptor beta isoform X1

    Conserved Domains (2) summary
    cd06937
    Location:186416
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cd06964
    Location:82166
    NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
  2. XM_038570691.1XP_038426619.1  retinoic acid receptor beta isoform X4

    Conserved Domains (2) summary
    cd06937
    Location:67297
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:147
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
  3. XM_038570688.1XP_038426616.1  retinoic acid receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A8C0PKW1, A0A8C0R7A9, A0A8I3PGE5
    Conserved Domains (2) summary
    cd06937
    Location:179409
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cd06964
    Location:75159
    NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
  4. XM_038570690.1XP_038426618.1  retinoic acid receptor beta isoform X4

    Conserved Domains (2) summary
    cd06937
    Location:67297
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:147
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
  5. XM_038570689.1XP_038426617.1  retinoic acid receptor beta isoform X3

    Conserved Domains (2) summary
    cd06937
    Location:81311
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:561
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006605.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    18204235..18714201 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003433127.5XP_003433175.1  retinoic acid receptor beta isoform X1

    See identical proteins and their annotated locations for XP_003433175.1

    Conserved Domains (2) summary
    cd06937
    Location:186416
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cd06964
    Location:82166
    NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
  2. XM_005634353.4XP_005634410.1  retinoic acid receptor beta isoform X4

    Conserved Domains (2) summary
    cd06937
    Location:67297
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:147
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
  3. XM_845662.6XP_850755.1  retinoic acid receptor beta isoform X2

    See identical proteins and their annotated locations for XP_850755.1

    UniProtKB/TrEMBL
    A0A8C0PKW1, A0A8C0R7A9, A0A8I3PGE5
    Conserved Domains (2) summary
    cd06937
    Location:179409
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cd06964
    Location:75159
    NR_DBD_RAR; DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers
  4. XM_014106585.3XP_013962060.1  retinoic acid receptor beta isoform X4

    Conserved Domains (2) summary
    cd06937
    Location:67297
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:147
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
  5. XM_022408569.2XP_022264277.1  retinoic acid receptor beta isoform X3

    Conserved Domains (2) summary
    cd06937
    Location:81311
    NR_LBD_RAR; The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily
    cl02596
    Location:561
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers