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ILK integrin linked kinase [ Canis lupus familiaris (dog) ]

Gene ID: 476836, updated on 4-Nov-2022

Summary

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Official Symbol
ILKprovided by VGNC
Official Full Name
integrin linked kinaseprovided by VGNC
Primary source
VGNC:VGNC:42001
See related
Ensembl:ENSCAFG00845008689
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See ILK in Genome Data Viewer
Location:
chromosome: 21
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (30737472..30744133)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (29613150..29619814)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (30419226..30425893)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (30058249..30064907)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (30223907..30230574)
105 previous assembly CanFam3.1 (GCF_000002285.3) 21 NC_006603.3 (29911326..29917972)

Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene dynein heavy chain domain 1 Neighboring gene uncharacterized LOC119864994 Neighboring gene ribosomal RNA processing 8 Neighboring gene TATA-box binding protein associated factor 10 Neighboring gene tripeptidyl peptidase 1 Neighboring gene dachsous cadherin-related 1 Neighboring gene uncharacterized LOC111091544

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Integrin-linked kinase regulates smooth muscle differentiation marker gene expression in airway tissue. Wu Y, et al. Am J Physiol Lung Cell Mol Physiol, 2008 Dec. PMID 18805960, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

General protein information

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Preferred Names
integrin-linked protein kinase
XP_022263486.1
XP_038286300.1
XP_038286301.1
XP_038286302.1
XP_038286303.1
XP_038312258.1
XP_038312259.1
XP_038361628.1
XP_038361629.1
XP_038361630.1
XP_038361631.1
XP_038424837.1
XP_038424838.1
XP_038424839.1
XP_038424840.1
XP_038489002.1
XP_038489003.1
XP_038489004.1
XP_038489005.1
XP_534040.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051825.1 Reference ROS_Cfam_1.0

    Range
    30737472..30744133
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038430372.1 → XP_038286300.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KAB5, A0A8C0RXS6, A0A8I3N6J1
    Related
    ENSCAFP00845011870.1, ENSCAFT00845015287.1
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_038430374.1 → XP_038286302.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KAB5, A0A8C0RXS6, A0A8I3N6J1
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_038430373.1 → XP_038286301.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0KAB5, A0A8C0RXS6, A0A8I3N6J1
    Related
    ENSCAFP00845011903.1, ENSCAFT00845015333.1
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_038430375.1 → XP_038286303.1  integrin-linked protein kinase isoform X2

    Conserved Domains (3) summary
    cd14057
    Location:171 → 422
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:6 → 37
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:11 → 97
    Ank_2; Ankyrin repeats (3 copies)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049281.1 Alternate UMICH_Zoey_3.1

    Range
    30058249..30064907
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038505700.1 → XP_038361628.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_038505702.1 → XP_038361630.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_038505701.1 → XP_038361629.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_038505703.1 → XP_038361631.1  integrin-linked protein kinase isoform X2

    Conserved Domains (3) summary
    cd14057
    Location:171 → 422
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:6 → 37
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:11 → 97
    Ank_2; Ankyrin repeats (3 copies)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

    Range
    30223907..30230574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038633074.1 → XP_038489002.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_038633076.1 → XP_038489004.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_038633075.1 → XP_038489003.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_038633077.1 → XP_038489005.1  integrin-linked protein kinase isoform X2

    Conserved Domains (3) summary
    cd14057
    Location:171 → 422
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:6 → 37
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:11 → 97
    Ank_2; Ankyrin repeats (3 copies)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

    Range
    30419226..30425893
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038568909.1 → XP_038424837.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_038568911.1 → XP_038424839.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_038568910.1 → XP_038424838.1  integrin-linked protein kinase isoform X1

    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_038568912.1 → XP_038424840.1  integrin-linked protein kinase isoform X2

    Conserved Domains (3) summary
    cd14057
    Location:171 → 422
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:6 → 37
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:11 → 97
    Ank_2; Ankyrin repeats (3 copies)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    29613150..29619814
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_534040.7 → XP_534040.1  integrin-linked protein kinase isoform X1

    See identical proteins and their annotated locations for XP_534040.1

    UniProtKB/TrEMBL
    A0A8C0NGM4, A0A8P0TU48, E2R5H4
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_022407778.2 → XP_022263486.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0NGM4, A0A8P0TU48
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_038456330.1 → XP_038312258.1  integrin-linked protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C0NGM4, A0A8P0TU48
    Conserved Domains (4) summary
    cd14057
    Location:198 → 449
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:33 → 64
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:4 → 54
    Ank_4; Ankyrin repeats (many copies)
    pfam12796
    Location:38 → 124
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_038456331.1 → XP_038312259.1  integrin-linked protein kinase isoform X2

    Conserved Domains (3) summary
    cd14057
    Location:171 → 422
    PK_ILK; Pseudokinase domain of Integrin Linked Kinase
    sd00045
    Location:6 → 37
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:11 → 97
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
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