U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

FCHO1 FCH and mu domain containing endocytic adaptor 1 [ Canis lupus familiaris (dog) ]

Gene ID: 476673, updated on 25-Jul-2026
Official Symbol
FCHO1provided by VGNC
Official Full Name
FCH and mu domain containing endocytic adaptor 1provided by VGNC
Primary source
VGNC:VGNC:40804
See related
Ensembl:ENSCAFG00845025423 RGD:12267910
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See FCHO1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
29
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (45592304..45619706, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (45019095..45046487, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (45514775..45541666, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (44828688..44855626, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (45238727..45266142, complement)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene insulin like 3 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 Neighboring gene uncharacterized LOC111091358 Neighboring gene microtubule associated protein 1S Neighboring gene unc-13 homolog A

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in clathrin coat assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in clathrin-dependent endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in clathrin-coated pit IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in clathrin-coated vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
F-BAR domain only protein 1
Names
FCH domain only 1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    45592304..45619706 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038428219.1 → XP_038284147.1  F-BAR domain only protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A8C0KHF3
    Conserved Domains (2) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    cl10970
    Location:523 → 784
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  2. XM_038428218.1 → XP_038284146.1  F-BAR domain only protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0KHF3
    Conserved Domains (2) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    cl10970
    Location:533 → 794
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  3. XM_038428214.1 → XP_038284142.1  F-BAR domain only protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KHF3
    Related
    ENSCAFP00845035328.1, ENSCAFT00845045066.1
    Conserved Domains (3) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    PHA03307
    Location:301 → 564
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:615 → 876
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  4. XM_038428211.1 → XP_038284139.1  F-BAR domain only protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KHF3, A0A8I3PR98
    Related
    ENSCAFP00845035699.1, ENSCAFT00845045509.1
    Conserved Domains (3) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    PHA03307
    Location:301 → 529
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:625 → 886
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  5. XM_038428217.1 → XP_038284145.1  F-BAR domain only protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PQU0
    Conserved Domains (3) summary
    PHA03307
    Location:228 → 456
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:552 → 813
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    cl12013
    Location:6 → 196
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  6. XM_038428215.1 → XP_038284143.1  F-BAR domain only protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PQU0
    Conserved Domains (3) summary
    PHA03307
    Location:251 → 479
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:575 → 836
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    cl12013
    Location:1 → 219
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  7. XM_038428212.1 → XP_038284140.1  F-BAR domain only protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KHF3, A0A8I3PR98
    Conserved Domains (3) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    PHA03307
    Location:301 → 529
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:625 → 886
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  8. XM_038428216.1 → XP_038284144.1  F-BAR domain only protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PQU0
    Related
    ENSCAFP00845035530.1, ENSCAFT00845045305.1
    Conserved Domains (3) summary
    PHA03307
    Location:251 → 479
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:575 → 836
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    cl12013
    Location:1 → 219
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    44828688..44855626 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038503864.1 → XP_038359792.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    45238727..45266142 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038631042.1 → XP_038486970.1  

    Conserved Domains (2) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    cl10970
    Location:523 → 784
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  2. XM_038631041.1 → XP_038486969.1  

    Conserved Domains (2) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    cl10970
    Location:533 → 794
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  3. XM_038631037.1 → XP_038486965.1  

    Conserved Domains (3) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    PHA03307
    Location:301 → 564
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:615 → 876
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  4. XM_038631035.1 → XP_038486963.1  

    Conserved Domains (3) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    PHA03307
    Location:301 → 529
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:625 → 886
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  5. XM_038631040.1 → XP_038486968.1  

    Conserved Domains (3) summary
    PHA03307
    Location:228 → 456
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:552 → 813
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    cl12013
    Location:6 → 196
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  6. XM_038631038.1 → XP_038486966.1  

    Conserved Domains (3) summary
    PHA03307
    Location:251 → 479
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:575 → 836
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    cl12013
    Location:1 → 219
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  7. XM_038631036.1 → XP_038486964.1  

    Conserved Domains (3) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    PHA03307
    Location:301 → 529
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:625 → 886
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  8. XM_038631039.1 → XP_038486967.1  

    Conserved Domains (3) summary
    PHA03307
    Location:251 → 479
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:575 → 836
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    cl12013
    Location:1 → 219
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    45514775..45541666 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038566888.1 → XP_038422816.1  F-BAR domain only protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A8C0KHF3

  2. XM_038566887.1 → XP_038422815.1  F-BAR domain only protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0KHF3

  3. XM_038566883.1 → XP_038422811.1  F-BAR domain only protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KHF3

  4. XM_038566881.1 → XP_038422809.1  F-BAR domain only protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KHF3

  5. XM_038566886.1 → XP_038422814.1  F-BAR domain only protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PQU0

  6. XM_038566884.1 → XP_038422812.1  F-BAR domain only protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PQU0

  7. XM_038566882.1 → XP_038422810.1  F-BAR domain only protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KHF3

  8. XM_038566885.1 → XP_038422813.1  F-BAR domain only protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PQU0

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    45019095..45046487 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038455691.1 → XP_038311619.1  F-BAR domain only protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A8C0KHF3
    Conserved Domains (2) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    cl10970
    Location:523 → 784
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  2. XM_038455690.1 → XP_038311618.1  F-BAR domain only protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C0KHF3
    Conserved Domains (2) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    cl10970
    Location:533 → 794
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  3. XM_038455687.1 → XP_038311615.1  F-BAR domain only protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KHF3
    Conserved Domains (3) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    PHA03307
    Location:301 → 564
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:615 → 876
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  4. XM_038455686.1 → XP_038311614.1  F-BAR domain only protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KHF3, A0A8I3PR98
    Conserved Domains (3) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    PHA03307
    Location:301 → 529
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:625 → 886
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  5. XM_038455689.1 → XP_038311617.1  F-BAR domain only protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I3PQU0
    Conserved Domains (3) summary
    PHA03307
    Location:228 → 456
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:552 → 813
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    cl12013
    Location:6 → 196
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  6. XM_022406888.2 → XP_022262596.1  F-BAR domain only protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PQU0
    Conserved Domains (3) summary
    PHA03307
    Location:251 → 479
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:575 → 836
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    cl12013
    Location:1 → 219
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  7. XM_014122301.3 → XP_013977776.1  F-BAR domain only protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KHF3, A0A8I3PR98
    Conserved Domains (3) summary
    cd07674
    Location:10 → 269
    F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
    PHA03307
    Location:301 → 529
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:625 → 886
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

  8. XM_038455688.1 → XP_038311616.1  F-BAR domain only protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8I3PQU0
    Conserved Domains (3) summary
    PHA03307
    Location:251 → 479
    PHA03307; transcriptional regulator ICP4; Provisional
    cl10970
    Location:575 → 836
    AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
    cl12013
    Location:1 → 219
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials