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LAMB2 laminin subunit beta 2 [ Canis lupus familiaris (dog) ]

Gene ID: 476626, updated on 27-Jun-2026
Official Symbol
LAMB2provided by VGNC
Official Full Name
laminin subunit beta 2provided by VGNC
Primary source
VGNC:VGNC:42568
See related
Ensembl:ENSCAFG00845027640 RGD:12331778
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See LAMB2 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
39
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (40388459..40419510)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (39949768..39980800)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (40439108..40470170)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (39759167..39786363)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (40158837..40189873)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene chromosome 20 C3orf84 homolog Neighboring gene kelch domain containing 8B Neighboring gene coiled-coil domain containing 71 Neighboring gene ubiquitin specific peptidase 19 Neighboring gene glutaminyl-tRNA synthetase 1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
laminin subunit beta-2
Names
laminin, gamma 1 (formerly LAMB2)
XP_038359385.1

Length

  • 1874

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    40388459..40419510
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038427780.1 → XP_038283708.1  laminin subunit beta-2 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q2E4
    Related
    ENSCAFP00845038430.1, ENSCAFT00845048988.1
    Conserved Domains (6) summary
    smart00180
    Location:825 → 870
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:563 → 604
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    TIGR02168
    Location:1249 → 1838
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00053
    Location:1191 → 1238
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:90 → 323
    Laminin_N; Laminin N-terminal (Domain VI)
    cd22299
    Location:1775 → 1846
    cc_LAMB2_C; C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2)

  2. XM_038427775.1 → XP_038283703.1  laminin subunit beta-2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q2E4
    Conserved Domains (6) summary
    PRK02224
    Location:1544 → 1863
    PRK02224; DNA double-strand break repair Rad50 ATPase
    smart00180
    Location:859 → 904
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:597 → 638
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1225 → 1272
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:124 → 357
    Laminin_N; Laminin N-terminal (Domain VI)
    cd22299
    Location:1809 → 1880
    cc_LAMB2_C; C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2)

  3. XM_038427777.1 → XP_038283705.1  laminin subunit beta-2 isoform X3

    UniProtKB/TrEMBL
    A0A8I3Q2E4
    Conserved Domains (6) summary
    PRK02224
    Location:1538 → 1857
    PRK02224; DNA double-strand break repair Rad50 ATPase
    smart00180
    Location:859 → 904
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:597 → 638
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1219 → 1266
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:124 → 357
    Laminin_N; Laminin N-terminal (Domain VI)
    cd22299
    Location:1803 → 1874
    cc_LAMB2_C; C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2)

  4. XM_038427778.1 → XP_038283706.1  laminin subunit beta-2 isoform X4

    UniProtKB/TrEMBL
    A0A8I3Q2E4
    Conserved Domains (6) summary
    PRK02224
    Location:1535 → 1854
    PRK02224; DNA double-strand break repair Rad50 ATPase
    smart00180
    Location:850 → 895
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:588 → 629
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1216 → 1263
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:115 → 348
    Laminin_N; Laminin N-terminal (Domain VI)
    cd22299
    Location:1800 → 1871
    cc_LAMB2_C; C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2)

  5. XM_038427776.1 → XP_038283704.1  laminin subunit beta-2 isoform X2

    UniProtKB/TrEMBL
    A0A8I3Q2E4
    Conserved Domains (6) summary
    PRK02224
    Location:1542 → 1861
    PRK02224; DNA double-strand break repair Rad50 ATPase
    smart00180
    Location:857 → 902
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:595 → 636
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1223 → 1270
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:122 → 355
    Laminin_N; Laminin N-terminal (Domain VI)
    cd22299
    Location:1807 → 1878
    cc_LAMB2_C; C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2)

  6. XM_038427781.1 → XP_038283709.1  laminin subunit beta-2 isoform X7

    UniProtKB/TrEMBL
    A0A8C0R508
    Conserved Domains (6) summary
    smart00180
    Location:745 → 790
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:483 → 524
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    TIGR02168
    Location:1169 → 1758
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00053
    Location:1111 → 1158
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:10 → 243
    Laminin_N; Laminin N-terminal (Domain VI)
    cd22299
    Location:1695 → 1766
    cc_LAMB2_C; C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2)

  7. XM_038427779.1 → XP_038283707.1  laminin subunit beta-2 isoform X5

    UniProtKB/TrEMBL
    A0A8I3Q3S5
    Related
    ENSCAFP00845038590.1, ENSCAFT00845049179.1
    Conserved Domains (6) summary
    PRK02224
    Location:1520 → 1839
    PRK02224; DNA double-strand break repair Rad50 ATPase
    smart00180
    Location:835 → 880
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:573 → 614
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1201 → 1248
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:100 → 333
    Laminin_N; Laminin N-terminal (Domain VI)
    cd22299
    Location:1785 → 1856
    cc_LAMB2_C; C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2)

  8. XM_038427782.1 → XP_038283710.1  laminin subunit beta-2 isoform X8

    UniProtKB/TrEMBL
    A0A8C0R508
    Conserved Domains (6) summary
    smart00180
    Location:631 → 676
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:369 → 410
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    TIGR02168
    Location:1055 → 1644
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00053
    Location:997 → 1044
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:2 → 129
    Laminin_N; Laminin N-terminal (Domain VI)
    cd22299
    Location:1581 → 1652
    cc_LAMB2_C; C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    39759167..39786363
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038503457.1 → XP_038359385.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    40158837..40189873
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038630613.1 → XP_038486541.1  

  2. XM_038630608.1 → XP_038486536.1  

  3. XM_038630610.1 → XP_038486538.1  

  4. XM_038630611.1 → XP_038486539.1  

  5. XM_038630609.1 → XP_038486537.1  

  6. XM_038630614.1 → XP_038486542.1  

  7. XM_038630612.1 → XP_038486540.1  

  8. XM_038630615.1 → XP_038486543.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    40439108..40470170
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038566468.1 → XP_038422396.1  laminin subunit beta-2 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q2E4

  2. XM_038566463.1 → XP_038422391.1  laminin subunit beta-2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q2E4

  3. XM_038566465.1 → XP_038422393.1  laminin subunit beta-2 isoform X3

    UniProtKB/TrEMBL
    A0A8I3Q2E4

  4. XM_038566466.1 → XP_038422394.1  laminin subunit beta-2 isoform X4

    UniProtKB/TrEMBL
    A0A8I3Q2E4

  5. XM_038566464.1 → XP_038422392.1  laminin subunit beta-2 isoform X2

    UniProtKB/TrEMBL
    A0A8I3Q2E4

  6. XM_038566469.1 → XP_038422397.1  laminin subunit beta-2 isoform X7

    UniProtKB/TrEMBL
    A0A8C0R508

  7. XM_038566467.1 → XP_038422395.1  laminin subunit beta-2 isoform X5

    UniProtKB/TrEMBL
    A0A8I3Q3S5

  8. XM_038566470.1 → XP_038422398.1  laminin subunit beta-2 isoform X8

    UniProtKB/TrEMBL
    A0A8C0R508

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    39949768..39980800
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038455991.1 → XP_038311919.1  laminin subunit beta-2 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q2E4
    Conserved Domains (6) summary
    PRK02224
    Location:1510 → 1829
    PRK02224; DNA double-strand break repair Rad50 ATPase
    smart00180
    Location:825 → 870
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:563 → 604
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1191 → 1238
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:90 → 323
    Laminin_N; Laminin N-terminal (Domain VI)
    cd22299
    Location:1775 → 1846
    cc_LAMB2_C; C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2)

  2. XM_038455989.1 → XP_038311917.1  laminin subunit beta-2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q2E4
    Conserved Domains (6) summary
    PRK02224
    Location:1544 → 1863
    PRK02224; DNA double-strand break repair Rad50 ATPase
    smart00180
    Location:859 → 904
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:597 → 638
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1225 → 1272
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:124 → 357
    Laminin_N; Laminin N-terminal (Domain VI)
    cd22299
    Location:1809 → 1880
    cc_LAMB2_C; C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2)

  3. XM_038455990.1 → XP_038311918.1  laminin subunit beta-2 isoform X3

    UniProtKB/TrEMBL
    A0A8I3Q2E4
    Conserved Domains (6) summary
    PRK02224
    Location:1538 → 1857
    PRK02224; DNA double-strand break repair Rad50 ATPase
    smart00180
    Location:859 → 904
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:597 → 638
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1219 → 1266
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:124 → 357
    Laminin_N; Laminin N-terminal (Domain VI)
    cd22299
    Location:1803 → 1874
    cc_LAMB2_C; C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2)

  4. XM_022406743.2 → XP_022262451.1  laminin subunit beta-2 isoform X4

    UniProtKB/TrEMBL
    A0A8I3Q2E4
    Conserved Domains (6) summary
    smart00180
    Location:850 → 895
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:588 → 629
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1216 → 1255
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:128 → 348
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam08614
    Location:1277 → 1398
    ATG16; Autophagy protein 16 (ATG16)
    cl25732
    Location:1535 → 1854
    SMC_N; RecF/RecN/SMC N terminal domain

  5. XM_014121972.3 → XP_013977447.1  laminin subunit beta-2 isoform X2

    UniProtKB/TrEMBL
    A0A8I3Q2E4
    Conserved Domains (7) summary
    smart00180
    Location:857 → 902
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:595 → 636
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1223 → 1262
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:131 → 355
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam14346
    Location:1524 → 1593
    DUF4398; Domain of unknown function (DUF4398)
    pfam16731
    Location:1630 → 1845
    GARP; Glutamic acid/alanine-rich protein of Trypanosoma
    cl02193
    Location:1660 → 1839
    VirB5_like; VirB5 protein family

  6. XM_038455993.1 → XP_038311921.1  laminin subunit beta-2 isoform X7

    UniProtKB/TrEMBL
    A0A8C0R508
    Conserved Domains (6) summary
    PRK02224
    Location:1430 → 1749
    PRK02224; DNA double-strand break repair Rad50 ATPase
    smart00180
    Location:745 → 790
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:483 → 524
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1111 → 1158
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:10 → 243
    Laminin_N; Laminin N-terminal (Domain VI)
    cd22299
    Location:1695 → 1766
    cc_LAMB2_C; C-terminal coiled-coil domain found in laminin subunit beta-2 (LAMB2)

  7. XM_005632554.4 → XP_005632611.1  laminin subunit beta-2 isoform X5

    UniProtKB/TrEMBL
    A0A8I3Q3S5
    Conserved Domains (7) summary
    smart00180
    Location:835 → 880
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:573 → 614
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1201 → 1240
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:109 → 333
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam14346
    Location:1502 → 1571
    DUF4398; Domain of unknown function (DUF4398)
    pfam16731
    Location:1608 → 1823
    GARP; Glutamic acid/alanine-rich protein of Trypanosoma
    cl02193
    Location:1638 → 1817
    VirB5_like; VirB5 protein family

  8. XM_005632555.2 → XP_005632612.1  laminin subunit beta-2 isoform X8

    UniProtKB/TrEMBL
    A0A8C0R508
    Conserved Domains (7) summary
    smart00180
    Location:631 → 676
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:369 → 410
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:997 → 1036
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:2 → 129
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam14346
    Location:1298 → 1367
    DUF4398; Domain of unknown function (DUF4398)
    pfam16731
    Location:1404 → 1619
    GARP; Glutamic acid/alanine-rich protein of Trypanosoma
    cl02193
    Location:1434 → 1613
    VirB5_like; VirB5 protein family
Nucleotide Protein
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