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MARCO macrophage receptor with collagenous structure [ Canis lupus familiaris (dog) ]

Gene ID: 476117, updated on 25-Jul-2026
Official Symbol
MARCOprovided by VGNC
Official Full Name
macrophage receptor with collagenous structureprovided by VGNC
Primary source
VGNC:VGNC:54807
See related
Ensembl:ENSCAFG00845029094 RGD:12108127
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
Try the new Gene page
Try the new Transcripts and proteins table
See MARCO in Genome Data Viewer
Location:
chromosome: 19
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 19 NC_051823.1 (32381105..32426221, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 19 NC_006601.4 (31260569..31305455, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 19 NC_049240.1 (32420649..32465527, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 19 NC_049279.1 (31067312..31112187, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 19 NC_049760.1 (31233786..31278688, complement)

Chromosome 19 - NC_051823.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111091059 Neighboring gene complement C1q like 2 Neighboring gene engrailed homeobox 1 Neighboring gene transmembrane BAX inhibitor motif containing 6 pseudogene

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in endocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in intracellular anatomical structure IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
macrophage receptor MARCO

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051823.1 Reference ROS_Cfam_1.0

    Range
    32381105..32426221 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038426075.1XP_038282003.1  macrophage receptor MARCO isoform X2

    Conserved Domains (2) summary
    smart00202
    Location:327422
    SR; Scavenger receptor Cys-rich
    pfam01391
    Location:186242
    Collagen; Collagen triple helix repeat (20 copies)
  2. XM_038426074.1XP_038282002.1  macrophage receptor MARCO isoform X1

    UniProtKB/TrEMBL
    A0A8I3QIL7
    Related
    ENSCAFP00845040384.1, ENSCAFT00845051470.1
    Conserved Domains (2) summary
    smart00202
    Location:376471
    SR; Scavenger receptor Cys-rich
    pfam01391
    Location:235291
    Collagen; Collagen triple helix repeat (20 copies)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049279.1 Alternate UMICH_Zoey_3.1

    Range
    31067312..31112187 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038502264.1XP_038358192.1  

    Conserved Domains (2) summary
    smart00202
    Location:327422
    SR; Scavenger receptor Cys-rich
    pfam01391
    Location:186242
    Collagen; Collagen triple helix repeat (20 copies)
  2. XM_038502263.1XP_038358191.1  

    Conserved Domains (2) summary
    smart00202
    Location:376471
    SR; Scavenger receptor Cys-rich
    pfam01391
    Location:235291
    Collagen; Collagen triple helix repeat (20 copies)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049760.1 Alternate UNSW_CanFamBas_1.0

    Range
    31233786..31278688 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038629066.1XP_038484994.1  

    Conserved Domains (2) summary
    smart00202
    Location:327422
    SR; Scavenger receptor Cys-rich
    pfam01391
    Location:186242
    Collagen; Collagen triple helix repeat (20 copies)
  2. XM_038629065.1XP_038484993.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049240.1 Alternate UU_Cfam_GSD_1.0

    Range
    32420649..32465527 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038564978.1XP_038420906.1  macrophage receptor MARCO isoform X2

    Conserved Domains (2) summary
    smart00202
    Location:327422
    SR; Scavenger receptor Cys-rich
    pfam01391
    Location:186242
    Collagen; Collagen triple helix repeat (20 copies)
  2. XM_038564977.1XP_038420905.1  macrophage receptor MARCO isoform X1

    UniProtKB/TrEMBL
    A0A8I3QIL7
    Conserved Domains (2) summary
    smart00202
    Location:376471
    SR; Scavenger receptor Cys-rich
    pfam01391
    Location:235291
    Collagen; Collagen triple helix repeat (20 copies)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006601.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    31260569..31305455 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038454732.1XP_038310660.1  macrophage receptor MARCO isoform X2

    Conserved Domains (2) summary
    smart00202
    Location:327422
    SR; Scavenger receptor Cys-rich
    pfam01391
    Location:186242
    Collagen; Collagen triple helix repeat (20 copies)
  2. XM_005631917.4XP_005631974.1  macrophage receptor MARCO isoform X1

    Conserved Domains (2) summary
    pfam01391
    Location:238297
    Collagen; Collagen triple helix repeat (20 copies)
    smart00202
    Location:376471
    SR; Scavenger receptor Cys-rich