F11 coagulation factor XI [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: F11provided by VGNC
Official Full Name: coagulation factor XIprovided by VGNC
Primary source: VGNC:VGNC:40544
See related: Ensembl:ENSCAFG00845019228
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 16

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	16	NC_051820.1 (46683089..46700923, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	16	NC_006598.4 (44956542..44972975, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	16	NC_049237.1 (45395778..45412243, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	16	NC_049276.1 (44652096..44668510, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	16	NC_049757.1 (45264846..45281307, complement)
105	previous assembly	CanFam3.1 (GCF_000002285.3)	16	NC_006598.3 (44469609..44492833, complement)

Chromosome 16 - NC_051820.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

Homologs of the F11 gene: The F11 gene is conserved in human, chimpanzee, Rhesus monkey, cow, mouse, rat, chicken, and frog.
Orthologs

General protein information

Go to the top of the page Help

Preferred Names: coagulation factor XI

Names: plasma thromboplastin antecedent

NP_001128595.1

EC 3.4.21.27

XP_038544794.1

EC 3.4.21.27

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001135123.1 → NP_001128595.1 coagulation factor XI precursor

See identical proteins and their annotated locations for NP_001128595.1

Status: PROVISIONAL

Source sequence(s)

EU918291

UniProtKB/TrEMBL

B5LX43

Related

ENSCAFP00845026753.1, ENSCAFT00845034175.1

Conserved Domains (3) summary

smart00223
Location:199 → 282

APPLE; APPLE domain

smart00020
Location:386 → 617

Tryp_SPc; Trypsin-like serine protease

cd00190
Location:387 → 617

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051820.1 Reference ROS_Cfam_1.0

Range

46683089..46700923 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038688866.1 → XP_038544794.1 coagulation factor XI isoform X1

UniProtKB/TrEMBL

A0A8C0NKK8, A0A8I3P9T1

Related

ENSCAFP00845026653.1, ENSCAFT00845034051.1

Conserved Domains (2) summary

smart00223
Location:211 → 294

APPLE; APPLE domain

cd00190
Location:399 → 629

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...