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DDX60 DExD/H-box helicase 60 [ Canis lupus familiaris (dog) ]

Gene ID: 475493, updated on 27-Jun-2026
Official Symbol
DDX60provided by VGNC
Official Full Name
DExD/H-box helicase 60provided by VGNC
Primary source
VGNC:VGNC:54938
See related
Ensembl:ENSCAFG00845008534 RGD:12100017
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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Try the new Transcripts and proteins table
See DDX60 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
39
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (64515555..64608252, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (63841588..63933794, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (64122356..64214849, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (63738274..63830849, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (63734311..63826810, complement)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene annexin A10 Neighboring gene peptidyl-prolyl cis-trans isomerase FKBP3-like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC119868447 Neighboring gene uncharacterized LOC119869311 Neighboring gene uncharacterized LOC119869355

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
probable ATP-dependent RNA helicase DDX60
XP_013975221.2
XP_038306055.1
XP_038352691.1
XP_038415087.1
XP_038415088.1
XP_038415089.1
XP_038479034.1
XP_038479035.1
XP_038479036.1
XP_038544708.1
XP_038544709.1
XP_038544710.1
XP_532716.5

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    64515555..64608252 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038688781.1 → XP_038544709.1  probable ATP-dependent RNA helicase DDX60 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RW98, A0A8I3RWD3
    Related
    ENSCAFP00845011923.1, ENSCAFT00845015356.1
    Conserved Domains (3) summary
    PRK01172
    Location:1249 → 1513
    PRK01172; ATP-dependent DNA helicase
    COG4581
    Location:758 → 1369
    Dob10; Superfamily II RNA helicase [Replication, recombination and repair]
    cd18025
    Location:759 → 939
    DEXHc_DDX60; DEXH-box helicase domain of DEAD box protein 60

  2. XM_038688782.1 → XP_038544710.1  probable ATP-dependent RNA helicase DDX60 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NDA1, A0A8I3NMU2
    Related
    ENSCAFP00845012571.1, ENSCAFT00845016163.1
    Conserved Domains (3) summary
    PRK01172
    Location:1136 → 1400
    PRK01172; ATP-dependent DNA helicase
    COG4581
    Location:645 → 1256
    Dob10; Superfamily II RNA helicase [Replication, recombination and repair]
    cd18025
    Location:646 → 826
    DEXHc_DDX60; DEXH-box helicase domain of DEAD box protein 60

  3. XM_038688780.1 → XP_038544708.1  probable ATP-dependent RNA helicase DDX60 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RW98, A0A8I3RWD3
    Conserved Domains (3) summary
    PRK01172
    Location:1249 → 1513
    PRK01172; ATP-dependent DNA helicase
    COG4581
    Location:758 → 1369
    Dob10; Superfamily II RNA helicase [Replication, recombination and repair]
    cd18025
    Location:759 → 939
    DEXHc_DDX60; DEXH-box helicase domain of DEAD box protein 60

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    63738274..63830849 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038496763.1 → XP_038352691.1  

RNA

  1. XR_005337187.1 RNA Sequence

  2. XR_005337188.1 RNA Sequence

  3. XR_005337186.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    63734311..63826810 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038623107.1 → XP_038479035.1  

  2. XM_038623108.1 → XP_038479036.1  

  3. XM_038623106.1 → XP_038479034.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    64122356..64214849 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038559160.1 → XP_038415088.1  probable ATP-dependent RNA helicase DDX60 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RWD3

  2. XM_038559161.1 → XP_038415089.1  probable ATP-dependent RNA helicase DDX60 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NMU2

  3. XM_038559159.1 → XP_038415087.1  probable ATP-dependent RNA helicase DDX60 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RWD3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    63841588..63933794 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014119746.3 → XP_013975221.2  probable ATP-dependent RNA helicase DDX60 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RWD3
    Conserved Domains (3) summary
    PRK01172
    Location:1249 → 1513
    PRK01172; ATP-dependent DNA helicase
    COG4581
    Location:758 → 1369
    Dob10; Superfamily II RNA helicase [Replication, recombination and repair]
    cd18025
    Location:759 → 939
    DEXHc_DDX60; DEXH-box helicase domain of DEAD box protein 60

  2. XM_038450127.1 → XP_038306055.1  probable ATP-dependent RNA helicase DDX60 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NMU2
    Conserved Domains (3) summary
    PRK01172
    Location:1136 → 1400
    PRK01172; ATP-dependent DNA helicase
    COG4581
    Location:645 → 1256
    Dob10; Superfamily II RNA helicase [Replication, recombination and repair]
    cd18025
    Location:646 → 826
    DEXHc_DDX60; DEXH-box helicase domain of DEAD box protein 60

  3. XM_532716.7 → XP_532716.5  probable ATP-dependent RNA helicase DDX60 isoform X1

    UniProtKB/TrEMBL
    A0A8I3RWD3
    Conserved Domains (3) summary
    PRK01172
    Location:1249 → 1513
    PRK01172; ATP-dependent DNA helicase
    COG4581
    Location:758 → 1369
    Dob10; Superfamily II RNA helicase [Replication, recombination and repair]
    cd18025
    Location:759 → 939
    DEXHc_DDX60; DEXH-box helicase domain of DEAD box protein 60
Nucleotide Protein
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