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FNIP2 folliculin interacting protein 2 [ Canis lupus familiaris (dog) ]

Gene ID: 475482, updated on 4-Nov-2022

Summary

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Official Symbol
FNIP2provided by VGNC
Official Full Name
folliculin interacting protein 2provided by VGNC
Primary source
VGNC:VGNC:40936
See related
Ensembl:ENSCAFG00845011970
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See FNIP2 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
20
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (56573299..56706386)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (56192112..56324467)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (56225177..56357604)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (55853569..55944270)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (55911594..56043987)
105 previous assembly CanFam3.1 (GCF_000002285.3) 15 NC_006597.3 (55871782..55962676)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111090121 Neighboring gene uncharacterized LOC102157159 Neighboring gene chromosome 15 C4orf45 homolog Neighboring gene hsc70-interacting protein-like Neighboring gene uncharacterized LOC111098922

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A mutation in the canine gene encoding folliculin-interacting protein 2 (FNIP2) associated with a unique disruption in spinal cord myelination. Pemberton TJ, et al. Glia, 2014 Jan. PMID 24272703, Free PMC Article

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This study reported a mutation in the folliculin-interacting protein 2 gene in the Weimaraner dog that results in hypomyelination of the brain and a tract-specific myelin defect in the spinal cord.
    Title: A mutation in the canine gene encoding folliculin-interacting protein 2 (FNIP2) associated with a unique disruption in spinal cord myelination.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
folliculin-interacting protein 2; LOW QUALITY PROTEIN: folliculin-interacting protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    56573299..56706386
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038688729.1 → XP_038544657.1  folliculin-interacting protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8I3RZ15
    Related
    ENSCAFP00845016761.1, ENSCAFT00845021310.1
    Conserved Domains (3) summary
    pfam14636
    Location:49 → 162
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:325 → 558
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:964 → 1147
    FNIP_C; Folliculin-interacting protein C-terminus

  2. XM_038688728.1 → XP_038544656.1  folliculin-interacting protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NHG0
    Related
    ENSCAFP00845016863.1, ENSCAFT00845021457.1
    Conserved Domains (3) summary
    pfam14636
    Location:56 → 169
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:332 → 565
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:971 → 1154
    FNIP_C; Folliculin-interacting protein C-terminus

  3. XM_038688731.1 → XP_038544659.1  folliculin-interacting protein 2 isoform X5

    Conserved Domains (3) summary
    pfam14636
    Location:49 → 162
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:295 → 528
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:934 → 1117
    FNIP_C; Folliculin-interacting protein C-terminus

  4. XM_038688727.1 → XP_038544655.1  folliculin-interacting protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NHM0
    Related
    ENSCAFP00845016936.1, ENSCAFT00845021551.1
    Conserved Domains (3) summary
    pfam14636
    Location:70 → 183
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:346 → 579
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:985 → 1168
    FNIP_C; Folliculin-interacting protein C-terminus

  5. XM_038688730.1 → XP_038544658.1  folliculin-interacting protein 2 isoform X4

    Conserved Domains (3) summary
    pfam14636
    Location:70 → 183
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:316 → 549
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:955 → 1138
    FNIP_C; Folliculin-interacting protein C-terminus

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    55853569..55944270
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038496722.1 → XP_038352650.1  LOW QUALITY PROTEIN: folliculin-interacting protein 2 isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    55911594..56043987
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038623058.1 → XP_038478986.1  folliculin-interacting protein 2 isoform X2

    Conserved Domains (3) summary
    pfam14636
    Location:56 → 169
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:332 → 565
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:971 → 1154
    FNIP_C; Folliculin-interacting protein C-terminus

  2. XM_038623059.1 → XP_038478987.1  folliculin-interacting protein 2 isoform X3

    Conserved Domains (3) summary
    pfam14636
    Location:49 → 162
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:325 → 558
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:964 → 1147
    FNIP_C; Folliculin-interacting protein C-terminus

  3. XM_038623061.1 → XP_038478989.1  folliculin-interacting protein 2 isoform X5

    Conserved Domains (3) summary
    pfam14636
    Location:49 → 162
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:295 → 528
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:934 → 1117
    FNIP_C; Folliculin-interacting protein C-terminus

  4. XM_038623057.1 → XP_038478985.1  folliculin-interacting protein 2 isoform X1

  5. XM_038623060.1 → XP_038478988.1  folliculin-interacting protein 2 isoform X4

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    56225177..56357604
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038559116.1 → XP_038415044.1  folliculin-interacting protein 2 isoform X3

    Conserved Domains (3) summary
    pfam14636
    Location:49 → 162
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:325 → 558
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:964 → 1147
    FNIP_C; Folliculin-interacting protein C-terminus

  2. XM_038559115.1 → XP_038415043.1  folliculin-interacting protein 2 isoform X2

    Conserved Domains (3) summary
    pfam14636
    Location:56 → 169
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:332 → 565
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:971 → 1154
    FNIP_C; Folliculin-interacting protein C-terminus

  3. XM_038559118.1 → XP_038415046.1  folliculin-interacting protein 2 isoform X5

    Conserved Domains (3) summary
    pfam14636
    Location:49 → 162
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:295 → 528
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:934 → 1117
    FNIP_C; Folliculin-interacting protein C-terminus

  4. XM_038559114.1 → XP_038415042.1  folliculin-interacting protein 2 isoform X1

  5. XM_038559117.1 → XP_038415045.1  folliculin-interacting protein 2 isoform X4

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    56192112..56324467
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038452138.1 → XP_038308066.1  folliculin-interacting protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8I3RZ15
    Conserved Domains (3) summary
    pfam14636
    Location:49 → 162
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:325 → 558
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:964 → 1147
    FNIP_C; Folliculin-interacting protein C-terminus

  2. XM_038452137.1 → XP_038308065.1  folliculin-interacting protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8I3NHG0
    Conserved Domains (3) summary
    pfam14636
    Location:56 → 169
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:332 → 565
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:971 → 1154
    FNIP_C; Folliculin-interacting protein C-terminus

  3. XM_038452139.1 → XP_038308067.1  folliculin-interacting protein 2 isoform X5

    Conserved Domains (3) summary
    pfam14636
    Location:49 → 162
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:295 → 528
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:934 → 1117
    FNIP_C; Folliculin-interacting protein C-terminus

  4. XM_005629382.4 → XP_005629439.1  folliculin-interacting protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8P0TG57
    Conserved Domains (3) summary
    pfam14636
    Location:70 → 183
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:346 → 579
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:985 → 1168
    FNIP_C; Folliculin-interacting protein C-terminus

  5. XM_005629383.4 → XP_005629440.1  folliculin-interacting protein 2 isoform X4

    Conserved Domains (3) summary
    pfam14636
    Location:70 → 183
    FNIP_N; Folliculin-interacting protein N-terminus
    pfam14637
    Location:316 → 549
    FNIP_M; Folliculin-interacting protein middle domain
    pfam14638
    Location:955 → 1138
    FNIP_C; Folliculin-interacting protein C-terminus
Nucleotide Protein
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