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LIN7A lin-7 homolog A, crumbs cell polarity complex component [ Canis lupus familiaris (dog) ]

Gene ID: 475412, updated on 25-Jul-2026
Official Symbol
LIN7Aprovided by VGNC
Official Full Name
lin-7 homolog A, crumbs cell polarity complex componentprovided by VGNC
Primary source
VGNC:VGNC:42686
See related
Ensembl:ENSCAFG00845009762 RGD:12197582
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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See LIN7A in Genome Data Viewer
Location:
chromosome: 15
Exon count:
8
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (23466000..23590006, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (23528909..23652711, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (23343341..23467440, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (23043326..23167286, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (23102924..23227023, complement)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene myogenic factor 6 Neighboring gene myogenic factor 5 Neighboring gene uncharacterized LOC119869337 Neighboring gene acyl-CoA synthetase short chain family member 3 Neighboring gene PTPRF interacting protein alpha 2 Neighboring gene uncharacterized LOC111099022

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L27 domain binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in maintenance of epithelial cell apical/basal polarity IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in neurotransmitter secretion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein localization to basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of MPP7-DLG1-LIN7 complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cell-cell junction IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
protein lin-7 homolog A

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    23466000..23590006 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038688124.1XP_038544052.1  protein lin-7 homolog A

    UniProtKB/TrEMBL
    A0A8C0KUF1, A0A8I3N7Y5
    Related
    ENSCAFP00845013401.1, ENSCAFT00845017196.1
    Conserved Domains (2) summary
    smart00569
    Location:3183
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:106187
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    23043326..23167286 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038496138.1XP_038352066.1  

    Conserved Domains (2) summary
    smart00569
    Location:3183
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:106187
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    23102924..23227023 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038622430.1XP_038478358.1  

    Conserved Domains (2) summary
    smart00569
    Location:3183
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:106187
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    23343341..23467440 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038558536.1XP_038414464.1  protein lin-7 homolog A

    UniProtKB/TrEMBL
    A0A8C0KUF1, A0A8I3N7Y5
    Conserved Domains (2) summary
    smart00569
    Location:3183
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:106187
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    23528909..23652711 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038451863.1XP_038307791.1  protein lin-7 homolog A

    UniProtKB/TrEMBL
    A0A8C0KUF1, A0A8I3N7Y5
    Conserved Domains (2) summary
    smart00569
    Location:3183
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:106187
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...