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CAV2 caveolin 2 [ Canis lupus familiaris (dog) ]

Gene ID: 475294, updated on 17-Nov-2020

Summary

Official Symbol
CAV2provided by VGNC
Official Full Name
caveolin 2provided by VGNC
Primary source
VGNC:VGNC:38752
See related
Ensembl:ENSCAFG00000003402
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
CAV-2
Orthologs

Genomic context

See CAV2 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
3
Annotation release Status Assembly Chr Location
105 current CanFam3.1 (GCF_000002285.3) 14 NC_006596.3 (55437622..55445481)

Chromosome 14 - NC_006596.3Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein E pseudogene Neighboring gene testin LIM domain protein Neighboring gene uncharacterized LOC111098847 Neighboring gene caveolin 1 Neighboring gene MET proto-oncogene, receptor tyrosine kinase Neighboring gene uncharacterized LOC111098848

Genomic regions, transcripts, and products

Genomic Sequence:
NC_006596.3 Chromosome 14 Reference CanFam3.1 Primary Assembly

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
D1 dopamine receptor binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein-macromolecule adaptor activity IEA
Inferred from Electronic Annotation
more info
 
scaffold protein binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
basement membrane organization IEA
Inferred from Electronic Annotation
more info
 
caveola assembly ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
endoplasmic reticulum organization ISS
Inferred from Sequence or Structural Similarity
more info
 
mitochondrion organization ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of endothelial cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
positive regulation by host of viral release from host cell IEA
Inferred from Electronic Annotation
more info
 
positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 
positive regulation of dopamine receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
positive regulation of endothelial cell proliferation IEA
Inferred from Electronic Annotation
more info
 
receptor-mediated endocytosis of virus by host cell IEA
Inferred from Electronic Annotation
more info
 
regulation of mitotic nuclear division IEA
Inferred from Electronic Annotation
more info
 
skeletal muscle fiber development ISS
Inferred from Sequence or Structural Similarity
more info
 
vesicle docking ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
vesicle fusion ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
acrosomal membrane IEA
Inferred from Electronic Annotation
more info
 
caveola ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
caveolar macromolecular signaling complex IEA
Inferred from Electronic Annotation
more info
 
extrinsic component of cytoplasmic side of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
transport vesicle IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001010997.3NP_001010997.2  caveolin-2

    See identical proteins and their annotated locations for NP_001010997.2

    Status: PROVISIONAL

    Source sequence(s)
    DP000236
    UniProtKB/Swiss-Prot
    O46550
    Related
    ENSCAFP00000038932.1, ENSCAFT00000048990.2
    Conserved Domains (1) summary
    pfam01146
    Location:39160
    Caveolin; Caveolin

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006596.3 Reference CanFam3.1 Primary Assembly

    Range
    55437622..55445481
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005628348.3XP_005628405.1  caveolin-2 isoform X1

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