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UBA6 ubiquitin like modifier activating enzyme 6 [ Canis lupus familiaris (dog) ]

Gene ID: 475160, updated on 25-Jul-2026
Official Symbol
UBA6provided by VGNC
Official Full Name
ubiquitin like modifier activating enzyme 6provided by VGNC
Primary source
VGNC:VGNC:48040
See related
Ensembl:ENSCAFG00845007757 RGD:12316525
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
UBE1L2
Orthologs
Try the new Gene page
Try the new Transcripts and proteins table
See UBA6 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
34
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (58760633..58843785, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (58064591..58146589, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (58987100..59069355, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (58486500..58568429, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (57976685..58058696, complement)

Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene centromere protein C Neighboring gene uncharacterized LOC111098632 Neighboring gene signal transducing adaptor family member 1 Neighboring gene uncharacterized LOC111098634 Neighboring gene gonadotropin releasing hormone receptor Neighboring gene transmembrane serine protease 11C Neighboring gene uncharacterized LOC111098635

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SUMO activating enzyme activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein sumoylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of SUMO activating enzyme complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
ubiquitin-like modifier-activating enzyme 6
Names
ubiquitin-activating enzyme E1-like 2
XP_005628302.1
XP_038349839.1

Length

  • 1052
XP_038412125.1
XP_038412126.1
XP_038476058.1
XP_038476059.1
XP_038541695.1
XP_038541696.1
XP_532390.2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051817.1 Reference ROS_Cfam_1.0

    Range
    58760633..58843785 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038685767.1XP_038541695.1  ubiquitin-like modifier-activating enzyme 6 isoform X1

    UniProtKB/TrEMBL
    A0A8I3N4B5, A0A8I3NJW4
    Related
    ENSCAFP00845010946.1, ENSCAFT00845014124.1
    Conserved Domains (1) summary
    TIGR01408
    Location:381046
    Ube1; ubiquitin-activating enzyme E1
  2. XM_038685768.1XP_038541696.1  ubiquitin-like modifier-activating enzyme 6 isoform X2

    UniProtKB/TrEMBL
    A0A8I3N8D3
    Related
    ENSCAFP00845011379.1, ENSCAFT00845014687.1
    Conserved Domains (1) summary
    TIGR01408
    Location:71015
    Ube1; ubiquitin-activating enzyme E1

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049273.1 Alternate UMICH_Zoey_3.1

    Range
    58486500..58568429 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038493911.1XP_038349839.1  

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

    Range
    57976685..58058696 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038620130.1XP_038476058.1  

  2. XM_038620131.1XP_038476059.1  

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

    Range
    58987100..59069355 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038556197.1XP_038412125.1  ubiquitin-like modifier-activating enzyme 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LTS0, A0A8I3NJW4
  2. XM_038556198.1XP_038412126.1  ubiquitin-like modifier-activating enzyme 6 isoform X2

    UniProtKB/TrEMBL
    A0A8I3N8D3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    58064591..58146589 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_532390.7XP_532390.2  ubiquitin-like modifier-activating enzyme 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LTS0, A0A8I3NJW4
    Conserved Domains (1) summary
    cl25380
    Location:381046
    ThiF; ThiF family
  2. XM_005628245.4XP_005628302.1  ubiquitin-like modifier-activating enzyme 6 isoform X2

    UniProtKB/TrEMBL
    A0A8I3N8D3
    Conserved Domains (4) summary
    cd01490
    Location:431974
    Ube1_repeat2; Ubiquitin activating enzyme (E1), repeat 2. E1, a highly conserved small protein present universally in eukaryotic cells, is part of cascade to attach ubiquitin (Ub) covalently to substrate proteins. This cascade consists of activating (E1), conjugating ...
    cd01491
    Location:12401
    Ube1_repeat1; Ubiquitin activating enzyme (E1), repeat 1. E1, a highly conserved small protein present universally in eukaryotic cells, is part of cascade to attach ubiquitin (Ub) covalently to substrate proteins. This cascade consists of activating (E1), conjugating ...
    TIGR01408
    Location:71015
    Ube1; ubiquitin-activating enzyme E1
    pfam16191
    Location:268330
    E1_4HB; Ubiquitin-activating enzyme E1 four-helix bundle