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TONSL tonsoku like, DNA repair protein [ Canis lupus familiaris (dog) ]

Gene ID: 475127, updated on 25-Jul-2026
Official Symbol
TONSLprovided by VGNC
Official Full Name
tonsoku like, DNA repair proteinprovided by VGNC
Primary source
VGNC:VGNC:47710
See related
Ensembl:ENSCAFG00845010933 RGD:12140613
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
NFKBIL2
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See TONSL in Genome Data Viewer
Location:
chromosome: 13
Exon count:
25
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (38320076..38331667, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (37807109..37818700, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (38596909..38608509, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (38011918..38023454, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (38120565..38132086, complement)

Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 39 member 4 Neighboring gene VPS28 subunit of ESCRT-I Neighboring gene zinc finger TRAF-type and ring finger containing 1 Neighboring gene transmembrane protein 276

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
tonsoku-like protein
Names
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051817.1 Reference ROS_Cfam_1.0

    Range
    38320076..38331667 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038685371.1 → XP_038541299.1  tonsoku-like protein isoform X1

    UniProtKB/TrEMBL
    A0A8I3NHN2
    Conserved Domains (7) summary
    PHA03247
    Location:702 → 945
    PHA03247; large tegument protein UL36; Provisional
    COG0457
    Location:5 → 271
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00033
    Location:1031 → 1051
    LRR_RI; leucine-rich repeat [structural motif]
    sd00006
    Location:316 → 339
    TPR; TPR repeat [structural motif]
    sd00045
    Location:559 → 589
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:563 → 657
    Ank_2; Ankyrin repeats (3 copies)
    cl39015
    Location:1033 → 1296
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  2. XM_038685373.1 → XP_038541301.1  tonsoku-like protein isoform X3

    UniProtKB/TrEMBL
    A0A8I3NCG1
    Conserved Domains (8) summary
    PHA03247
    Location:481 → 724
    PHA03247; large tegument protein UL36; Provisional
    COG0457
    Location:9 → 197
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00033
    Location:810 → 830
    LRR_RI; leucine-rich repeat [structural motif]
    sd00006
    Location:95 → 118
    TPR; TPR repeat [structural motif]
    sd00045
    Location:338 → 368
    ANK; ANK repeat [structural motif]
    pfam13424
    Location:95 → 161
    TPR_12; Tetratricopeptide repeat
    pfam12796
    Location:342 → 436
    Ank_2; Ankyrin repeats (3 copies)
    cl39015
    Location:812 → 1075
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  3. XM_038685372.1 → XP_038541300.1  tonsoku-like protein isoform X2

    UniProtKB/TrEMBL
    A0A8I3NHN2
    Related
    ENSCAFP00845015114.1, ENSCAFT00845019332.1
    Conserved Domains (7) summary
    PHA03247
    Location:669 → 912
    PHA03247; large tegument protein UL36; Provisional
    COG0457
    Location:5 → 271
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00033
    Location:998 → 1018
    LRR_RI; leucine-rich repeat [structural motif]
    sd00006
    Location:316 → 339
    TPR; TPR repeat [structural motif]
    sd00045
    Location:526 → 556
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:530 → 624
    Ank_2; Ankyrin repeats (3 copies)
    cl39015
    Location:1000 → 1263
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

RNA

  1. XR_005436658.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049273.1 Alternate UMICH_Zoey_3.1

    Range
    38011918..38023454 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038493531.1 → XP_038349459.1  

  2. XM_038493533.1 → XP_038349461.1  

  3. XM_038493532.1 → XP_038349460.1  

RNA

  1. XR_005335151.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

    Range
    38120565..38132086 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038619761.1 → XP_038475689.1  

  2. XM_038619763.1 → XP_038475691.1  

  3. XM_038619762.1 → XP_038475690.1  

RNA

  1. XR_005403214.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

    Range
    38596909..38608509 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038555847.1 → XP_038411775.1  tonsoku-like protein isoform X1

    UniProtKB/TrEMBL
    A0A8I3NHN2
    Conserved Domains (7) summary
    PHA03247
    Location:702 → 945
    PHA03247; large tegument protein UL36; Provisional
    COG0457
    Location:5 → 271
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00033
    Location:1031 → 1051
    LRR_RI; leucine-rich repeat [structural motif]
    sd00006
    Location:316 → 339
    TPR; TPR repeat [structural motif]
    sd00045
    Location:559 → 589
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:563 → 657
    Ank_2; Ankyrin repeats (3 copies)
    cl39015
    Location:1033 → 1296
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  2. XM_038555849.1 → XP_038411777.1  tonsoku-like protein isoform X3

    UniProtKB/TrEMBL
    A0A8I3NCG1
    Conserved Domains (8) summary
    PHA03247
    Location:481 → 724
    PHA03247; large tegument protein UL36; Provisional
    COG0457
    Location:9 → 197
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00033
    Location:810 → 830
    LRR_RI; leucine-rich repeat [structural motif]
    sd00006
    Location:95 → 118
    TPR; TPR repeat [structural motif]
    sd00045
    Location:338 → 368
    ANK; ANK repeat [structural motif]
    pfam13424
    Location:95 → 161
    TPR_12; Tetratricopeptide repeat
    pfam12796
    Location:342 → 436
    Ank_2; Ankyrin repeats (3 copies)
    cl39015
    Location:812 → 1075
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  3. XM_038555848.1 → XP_038411776.1  tonsoku-like protein isoform X2

    UniProtKB/TrEMBL
    A0A8I3NHN2
    Conserved Domains (7) summary
    PHA03247
    Location:669 → 912
    PHA03247; large tegument protein UL36; Provisional
    COG0457
    Location:5 → 271
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00033
    Location:998 → 1018
    LRR_RI; leucine-rich repeat [structural motif]
    sd00006
    Location:316 → 339
    TPR; TPR repeat [structural motif]
    sd00045
    Location:526 → 556
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:530 → 624
    Ank_2; Ankyrin repeats (3 copies)
    cl39015
    Location:1000 → 1263
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

RNA

  1. XR_005368932.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    37807109..37818700 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038427292.1 → XP_038283220.1  tonsoku-like protein isoform X1

    UniProtKB/TrEMBL
    A0A8I3NHN2
    Conserved Domains (7) summary
    PHA03247
    Location:702 → 945
    PHA03247; large tegument protein UL36; Provisional
    COG0457
    Location:5 → 271
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00033
    Location:1031 → 1051
    LRR_RI; leucine-rich repeat [structural motif]
    sd00006
    Location:316 → 339
    TPR; TPR repeat [structural motif]
    sd00045
    Location:559 → 589
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:563 → 657
    Ank_2; Ankyrin repeats (3 copies)
    cl39015
    Location:1033 → 1296
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  2. XM_038427313.1 → XP_038283241.1  tonsoku-like protein isoform X3

    UniProtKB/TrEMBL
    A0A8I3NCG1
    Conserved Domains (8) summary
    PHA03247
    Location:481 → 724
    PHA03247; large tegument protein UL36; Provisional
    COG0457
    Location:9 → 197
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00033
    Location:810 → 830
    LRR_RI; leucine-rich repeat [structural motif]
    sd00006
    Location:95 → 118
    TPR; TPR repeat [structural motif]
    sd00045
    Location:338 → 368
    ANK; ANK repeat [structural motif]
    pfam13424
    Location:95 → 161
    TPR_12; Tetratricopeptide repeat
    pfam12796
    Location:342 → 436
    Ank_2; Ankyrin repeats (3 copies)
    cl39015
    Location:812 → 1075
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  3. XM_014118850.3 → XP_013974325.1  tonsoku-like protein isoform X2

    UniProtKB/TrEMBL
    A0A8I3NHN2
    Conserved Domains (7) summary
    PHA03247
    Location:669 → 912
    PHA03247; large tegument protein UL36; Provisional
    COG0457
    Location:5 → 271
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00033
    Location:998 → 1018
    LRR_RI; leucine-rich repeat [structural motif]
    sd00006
    Location:316 → 339
    TPR; TPR repeat [structural motif]
    sd00045
    Location:526 → 556
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:530 → 624
    Ank_2; Ankyrin repeats (3 copies)
    cl39015
    Location:1000 → 1263
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

RNA

  1. XR_005297873.1 RNA Sequence

Nucleotide Protein
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