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TXN2 thioredoxin 2 [ Canis lupus familiaris (dog) ]

Gene ID: 474519, updated on 27-Jun-2026
Official Symbol
TXN2provided by VGNC
Official Full Name
thioredoxin 2provided by VGNC
Primary source
VGNC:VGNC:48009
See related
Ensembl:ENSCAFG00845008715 RGD:12404087
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See TXN2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (28733351..28746338)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (27901673..27914661)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (28948151..28961119)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (28461701..28474674)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (28769602..28782587)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene FAD dependent oxidoreductase domain containing 2 Neighboring gene uncharacterized LOC111097833 Neighboring gene uncharacterized LOC111097834 Neighboring gene BET1 homolog

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Increase in Trx2/Prx3 redox system immunoreactivity in the spinal cord and hippocampus of aged dogs. Ahn JH, et al. Exp Gerontol, 2011 Nov. PMID 21871553
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein-disulfide reductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
thioredoxin, mitochondrial

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    28733351..28746338
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038679977.1 → XP_038535905.1  thioredoxin, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0QVC0
    Related
    ENSCAFT00845015322.1
    Conserved Domains (1) summary
    cl00388
    Location:66 → 162
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  2. XM_038679978.1 → XP_038535906.1  thioredoxin, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0QVC0
    Conserved Domains (1) summary
    cl00388
    Location:66 → 162
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    28461701..28474674
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038488722.1 → XP_038344650.1  

    Conserved Domains (1) summary
    cl00388
    Location:66 → 162
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  2. XM_038488723.1 → XP_038344651.1  

    Conserved Domains (1) summary
    cl00388
    Location:66 → 162
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    28769602..28782587
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038614616.1 → XP_038470544.1  

    Conserved Domains (1) summary
    cl00388
    Location:66 → 162
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  2. XM_038614617.1 → XP_038470545.1  

    Conserved Domains (1) summary
    cl00388
    Location:66 → 162
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    28948151..28961119
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038550687.1 → XP_038406615.1  thioredoxin, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0QVC0
    Conserved Domains (1) summary
    cl00388
    Location:66 → 162
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  2. XM_038550688.1 → XP_038406616.1  thioredoxin, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0QVC0
    Conserved Domains (1) summary
    cl00388
    Location:66 → 162
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    27901673..27914661
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014117372.2 → XP_013972847.1  thioredoxin, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0QVC0
    Conserved Domains (1) summary
    cl00388
    Location:66 → 162
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  2. XM_531748.6 → XP_531748.3  thioredoxin, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0QVC0
    Conserved Domains (1) summary
    cl00388
    Location:66 → 162
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
Nucleotide Protein
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