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Hcst hematopoietic cell signal transducer [ Rattus norvegicus (Norway rat) ]

Gene ID: 474146, updated on 18-Apr-2019

Summary

Official Symbol
Hcstprovided by RGD
Official Full Name
hematopoietic cell signal transducerprovided by RGD
Primary source
RGD:1359238
See related
Ensembl:ENSRNOG00000020849
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Dap10
Expression
Biased expression in Spleen (RPKM 41.5), Thymus (RPKM 34.6) and 7 other tissues See more
Orthologs

Genomic context

See Hcst in Genome Data Viewer
Location:
1q21
Exon count:
4
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (88879425..88881653, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (90035099..90037271, complement)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene similar to actin, gamma 2, smooth muscle, enteric Neighboring gene Tyro protein tyrosine kinase binding protein Neighboring gene NFKB inhibitor delta Neighboring gene amyloid beta precursor like protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
phosphatidylinositol 3-kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylinositol 3-kinase binding ISO
Inferred from Sequence Orthology
more info
PubMed 
signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
signaling receptor binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
positive regulation of phosphatidylinositol 3-kinase signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of phosphatidylinositol 3-kinase signaling ISO
Inferred from Sequence Orthology
more info
PubMed 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of immune response IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell surface ISO
Inferred from Sequence Orthology
more info
PubMed 
cell surface ISS
Inferred from Sequence or Structural Similarity
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
hematopoietic cell signal transducer
Names
DNAX-activation protein 10
membrane protein DAP10

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005900.1NP_001005900.1  hematopoietic cell signal transducer precursor

    See identical proteins and their annotated locations for NP_001005900.1

    Status: PROVISIONAL

    Source sequence(s)
    AY247020
    UniProtKB/Swiss-Prot
    Q6X9T8
    Related
    ENSRNOP00000028287.4, ENSRNOT00000028287.4
    Conserved Domains (1) summary
    pfam07213
    Location:179
    DAP10; DAP10 membrane protein

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    88879425..88881653 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006228785.3XP_006228847.1  hematopoietic cell signal transducer isoform X1

    Conserved Domains (1) summary
    pfam07213
    Location:178
    DAP10; DAP10 membrane protein

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    80049152..80051187 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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