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PLAT plasminogen activator, tissue type [ Pan troglodytes (chimpanzee) ]

Gene ID: 472748, updated on 3-Dec-2024
Official Symbol
PLATprovided by VGNC
Official Full Name
plasminogen activator, tissue typeprovided by VGNC
Primary source
VGNC:VGNC:3003
Locus tag
CK820_G0013033
See related
Ensembl:ENSPTRG00000020201
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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See PLAT in Genome Data Viewer
Location:
chromosome: 7
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 7 NC_072405.2 (50476722..50509295, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 8 NC_072406.1 (54056425..54074538, complement)

Chromosome 7 - NC_072405.2Genomic Context describing neighboring genes Neighboring gene lysine acetyltransferase 6A Neighboring gene small nucleolar RNA SNORD112 Neighboring gene adaptor related protein complex 3 subunit mu 2 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC129135606

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in plasminogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in platelet-derived growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in smooth muscle cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
tissue-type plasminogen activator
XP_003311748.1
XP_063672370.1
XP_063672371.1
XP_528120.3

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072405.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    50476722..50509295 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063816300.1 → XP_063672370.1  tissue-type plasminogen activator isoform X2

    UniProtKB/TrEMBL
    A0A2I3RAA6, A0A2I3RIE5, A0A2J8N7A9, A0A2J8N7B0, A0A6D2X8A6, A0A6D2XRP3

  2. XM_528120.8 → XP_528120.3  tissue-type plasminogen activator isoform X1

    See identical proteins and their annotated locations for XP_528120.3

    UniProtKB/TrEMBL
    A0A2I3RAA6, A0A2J8N7B0, A0A2J8N7D5, A0A6D2XRP3, A0A8I3B0K3, K7ATB3
    Related
    ENSPTRP00000061558.1
    Conserved Domains (5) summary
    smart00058
    Location:41 → 83
    FN1; Fibronectin type 1 domain
    cd00108
    Location:125 → 209
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd00190
    Location:313 → 559
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00008
    Location:86 → 117
    EGF; EGF-like domain
    pfam00051
    Location:215 → 296
    Kringle; Kringle domain

  3. XM_063816301.1 → XP_063672371.1  tissue-type plasminogen activator isoform X1

    UniProtKB/TrEMBL
    A0A2I3RAA6, A0A2J8N7B0, A0A2J8N7D5, A0A6D2XRP3, A0A8I3B0K3, K7ATB3

  4. XM_003311700.6 → XP_003311748.1  tissue-type plasminogen activator isoform X2

    See identical proteins and their annotated locations for XP_003311748.1

    UniProtKB/TrEMBL
    A0A2I3RAA6, A0A2I3RIE5, A0A2J8N7A9, A0A2J8N7B0, A0A6D2X8A6, A0A6D2XRP3
    Related
    ENSPTRP00000064409.1
    Conserved Domains (4) summary
    cd00108
    Location:79 → 163
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd00190
    Location:267 → 513
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00008
    Location:40 → 71
    EGF; EGF-like domain
    pfam00051
    Location:169 → 250
    Kringle; Kringle domain
Nucleotide Protein
Heading Accession and Version

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