PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PRKAA1provided by VGNC
Official Full Name: protein kinase AMP-activated catalytic subunit alpha 1provided by VGNC
Primary source: VGNC:VGNC:7113
Locus tag: CK820_G0035930
See related: Ensembl:ENSPTRG00000016821
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	4	NC_072402.2 (72010145..72050736)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	5	NC_072403.1 (72199491..72239983)

Chromosome 4 - NC_072402.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

STS-N23112 (e-PCR)
- UniSTS:79672

SGC34175 (e-PCR)
- UniSTS:65376

RH71041 (e-PCR)
- UniSTS:69251

NM_006251 (e-PCR)
- UniSTS:497561

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables AMP-activated protein kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 5'-AMP-activated protein kinase catalytic subunit alpha-1

Names: protein kinase, AMP-activated, alpha 1 catalytic subunit

XP_009447514.1

EC 2.7.1.-

EC 2.7.11.1

EC 2.7.11.26

EC 2.7.11.31

XP_016808849.1

EC 2.7.1.-

EC 2.7.11.1

EC 2.7.11.26

EC 2.7.11.31

XP_016808851.1

EC 2.7.1.-

EC 2.7.11.1

EC 2.7.11.26

EC 2.7.11.31

XP_024212393.1

EC 2.7.1.-

EC 2.7.11.1

EC 2.7.11.26

EC 2.7.11.31

XP_063667331.1

EC 2.7.1.-

EC 2.7.11.1

EC 2.7.11.26

EC 2.7.11.31

XP_063667332.1

EC 2.7.1.-

EC 2.7.11.1

EC 2.7.11.26

EC 2.7.11.31

XP_063667333.1

EC 2.7.1.-

EC 2.7.11.1

EC 2.7.11.26

EC 2.7.11.31

XP_063667334.1

EC 2.7.1.-

EC 2.7.11.1

EC 2.7.11.26

EC 2.7.11.31

XP_063667335.1

EC 2.7.1.-

EC 2.7.11.1

EC 2.7.11.26

EC 2.7.11.31

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

72010145..72050736

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009449239.5 → XP_009447514.1 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1

See identical proteins and their annotated locations for XP_009447514.1

UniProtKB/TrEMBL

A0A2J8QA77, A0A6D2VTX0, H2R5J1

Related

ENSPTRP00000048213.3

Conserved Domains (3) summary

cd12199
Location:419 → 572

AMPKA1_C; C-terminal regulatory domain of 5'-AMP-activated protein kinase (AMPK) alpha 1 catalytic subunit

cd14403
Location:311 → 375

UBA_AID_AAPK1; UBA-like autoinhibitory domain (AID) found in vertebrate 5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPKalpha-1)

cd14079
Location:24 → 294

STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase
XM_016953360.3 → XP_016808849.1 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X2

UniProtKB/TrEMBL

A0A2J8QA81, A0A6D2XY28, H2R5J0

Related

ENSPTRP00000048211.3

Conserved Domains (3) summary

cd12199
Location:404 → 557

AMPKA1_C; C-terminal regulatory domain of 5'-AMP-activated protein kinase (AMPK) alpha 1 catalytic subunit

cd14403
Location:296 → 360

UBA_AID_AAPK1; UBA-like autoinhibitory domain (AID) found in vertebrate 5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPKalpha-1)

cd14079
Location:24 → 279

STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase
XM_063811262.1 → XP_063667332.1 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X6
XM_063811264.1 → XP_063667334.1 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X8
XM_016953362.3 → XP_016808851.1 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X5
XM_063811265.1 → XP_063667335.1 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X8
XM_063811263.1 → XP_063667333.1 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X7
XM_024356625.3 → XP_024212393.1 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X4

Conserved Domains (3) summary

cd12199
Location:378 → 531

AMPKA1_C; C-terminal regulatory domain of 5'-AMP-activated protein kinase (AMPK) alpha 1 catalytic subunit

cd14403
Location:270 → 334

UBA_AID_AAPK1; UBA-like autoinhibitory domain (AID) found in vertebrate 5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPKalpha-1)

cd14079
Location:17 → 253

STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase
XM_063811261.1 → XP_063667331.1 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X3