U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ROCK2 Rho associated coiled-coil containing protein kinase 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 470307, updated on 3-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
ROCK2provided by VGNC
Official Full Name
Rho associated coiled-coil containing protein kinase 2provided by VGNC
Primary source
VGNC:VGNC:6655
Locus tag
CK820_G0009781
See related
Ensembl:ENSPTRG00000011658
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ROCK2 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
37
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 12 NC_072410.2 (111531332..111696946)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2A NC_072399.1 (11155301..11321906, complement)

Chromosome 12 - NC_072410.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104004880 Neighboring gene peptidyl-prolyl cis-trans isomerase A Neighboring gene axin interactor, dorsalization-associated protein-like Neighboring gene U6 spliceosomal RNA Neighboring gene solute carrier family 66 member 3 Neighboring gene chromosome 2A C2orf50 homolog Neighboring gene putative uncharacterized protein FLJ33534

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables Rho-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cortical actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in embryonic morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-threonine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of centrosome duplication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell junction assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in smooth muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
rho-associated protein kinase 2
XP_054534225.1
XP_054534226.1
XP_054534229.1
XP_054534230.1
XP_063645378.1
XP_063645379.1
XP_063645380.1
XP_063645381.1
XP_063645382.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072410.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    111531332..111696946
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063789312.1 → XP_063645382.1  rho-associated protein kinase 2 isoform X8

    UniProtKB/TrEMBL
    A0A2J8NLU6

  2. XM_054678255.2 → XP_054534230.1  rho-associated protein kinase 2 isoform X6

    UniProtKB/TrEMBL
    H2RCA0

  3. XM_063789309.1 → XP_063645379.1  rho-associated protein kinase 2 isoform X5

    UniProtKB/TrEMBL
    H2RCA0

  4. XM_063789308.1 → XP_063645378.1  rho-associated protein kinase 2 isoform X1

    UniProtKB/TrEMBL
    H2RCA0

  5. XM_054678250.2 → XP_054534225.1  rho-associated protein kinase 2 isoform X2

    UniProtKB/TrEMBL
    H2RCA0

  6. XM_054678251.2 → XP_054534226.1  rho-associated protein kinase 2 isoform X3

    UniProtKB/TrEMBL
    H2RCA0

  7. XM_054678254.2 → XP_054534229.1  rho-associated protein kinase 2 isoform X4

    UniProtKB/TrEMBL
    H2RCA0

  8. XM_063789311.1 → XP_063645381.1  rho-associated protein kinase 2 isoform X6

    UniProtKB/TrEMBL
    H2RCA0

  9. XM_063789310.1 → XP_063645380.1  rho-associated protein kinase 2 isoform X7

    UniProtKB/TrEMBL
    H2RCA0

RNA

  1. XR_010149192.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials