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CFTR CF transmembrane conductance regulator [ Pan troglodytes (chimpanzee) ]

Gene ID: 463674, updated on 29-Mar-2024

Summary

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Official Symbol
CFTRprovided by VGNC
Official Full Name
CF transmembrane conductance regulatorprovided by VGNC
Primary source
VGNC:VGNC:107818
Locus tag
CK820_G0011787
See related
Ensembl:ENSPTRG00000019619
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 6 NC_072404.2 (132861444..133044517)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (126912788..127095851)

Chromosome 6 - NC_072404.2Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain-containing protein 49-like Neighboring gene ankyrin repeat, SAM and basic leucine zipper domain containing 1 Neighboring gene uncharacterized LOC112209805 Neighboring gene cortactin binding protein 2 Neighboring gene serine/arginine-rich splicing factor 3-like Neighboring gene uncharacterized LOC107975927

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative analyses of multi-species sequences from targeted genomic regions. Thomas JW, et al. Nature, 2003 Aug 14. PMID 12917688

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chloride channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bicarbonate transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chloride transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cystic fibrosis transmembrane conductance regulator
Names
ATP-binding cassette sub-family C member 7
ATP-binding cassette transporter sub-family C member 7
cAMP-dependent chloride channel
channel conductance-controlling ATPase
cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)
NP_001073386.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079917.1 → NP_001073386.1  cystic fibrosis transmembrane conductance regulator

    See identical proteins and their annotated locations for NP_001073386.1

    Status: PROVISIONAL

    Source sequence(s)
    DP000016
    UniProtKB/Swiss-Prot
    Q2QLE5
    UniProtKB/TrEMBL
    A0A2J8QXC1, A0A2J8QXD7
    Related
    ENSPTRP00000033597.3, ENSPTRT00000036339.4
    Conserved Domains (1) summary
    TIGR01271
    Location:1 → 1480
    CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    132861444..133044517
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2QLE5.1 GenPept UniProtKB/Swiss-Prot:Q2QLE5

Gene LinkOut

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Molecular Biology Databases
Research Materials
Miscellaneous