Pglym87 Phosphoglyceromutase 87 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Pglym87provided by FlyBase
Official Full Name: Phosphoglyceromutase 87provided by FlyBase
Primary source: FLYBASE:FBgn0011270
Locus tag: Dmel_CG17645
See related: AllianceGenome:FB:FBgn0011270
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG17645; Dmel\CG17645; Pglym; pglym87
Summary: Predicted to enable bisphosphoglycerate mutase activity and phosphoglycerate mutase activity. Predicted to be involved in canonical glycolysis and gluconeogenesis. Predicted to be active in cytosol. Is expressed in adult head; elongation stage spermatid; primary spermatocyte; and spermatozoon. Human ortholog(s) of this gene implicated in myoglobinuria. Orthologous to several human genes including PGAM1 (phosphoglycerate mutase 1) and PGAM2 (phosphoglycerate mutase 2). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Try the new Transcripts and proteins table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (12231645..12232729, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (8057367..8058451, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables bisphosphoglycerate mutase activity	IEA Inferred from Electronic Annotation more info
enables bisphosphoglycerate mutase activity	ISS Inferred from Sequence or Structural Similarity more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables intramolecular phosphotransferase activity	IEA Inferred from Electronic Annotation more info
enables phosphoglycerate mutase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphoglycerate mutase activity	IEA Inferred from Electronic Annotation more info
enables phosphoglycerate mutase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in canonical glycolysis	IBA Inferred from Biological aspect of Ancestor more info
involved_in canonical glycolysis	ISS Inferred from Sequence or Structural Similarity more info
involved_in gluconeogenesis	ISS Inferred from Sequence or Structural Similarity more info
involved_in glycolytic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytosol	ISS Inferred from Sequence or Structural Similarity more info