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STING1 stimulator of interferon response cGAMP interactor 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 462107, updated on 3-Apr-2024

Summary

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Official Symbol
STING1provided by VGNC
Official Full Name
stimulator of interferon response cGAMP interactor 1provided by VGNC
Primary source
VGNC:VGNC:4202
Locus tag
CK820_G0047095
See related
Ensembl:ENSPTRG00000017301
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
TMEM173; STING-beta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (137192420..137200503, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (137211261..137218503, complement)

Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene endothelial cell surface expressed chemotaxis and apoptosis regulator Neighboring gene small integral membrane protein 33 Neighboring gene cancer-related nucleoside-triphosphatase-like Neighboring gene nuclear receptor coactivator 4-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel transcript isoform of STING that sequesters cGAMP and dominantly inhibits innate nucleic acid sensing. Wang PH, et al. Nucleic Acids Res, 2018 May 4. PMID 29547894, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2',3'-cyclic GMP-AMP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclic-di-GMP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in autophagosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macroautophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of type I interferon production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in reticulophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in autophagosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
stimulator of interferon genes protein
Names
transmembrane protein 173

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    137192420..137200503 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063811541.1 → XP_063667611.1  stimulator of interferon genes protein isoform X1

    UniProtKB/TrEMBL
    A0A2J8JIJ5, A0A5S6RD90, H2R3B4

  2. XM_063811540.1 → XP_063667610.1  stimulator of interferon genes protein isoform X1

    UniProtKB/TrEMBL
    A0A2J8JIJ5, A0A5S6RD90, H2R3B4

  3. XM_001135484.6 → XP_001135484.1  stimulator of interferon genes protein isoform X1

    See identical proteins and their annotated locations for XP_001135484.1

    UniProtKB/TrEMBL
    A0A2J8JIJ5, A0A5S6RD90, H2R3B4
    Related
    ENSPTRP00000045233.4
    Conserved Domains (1) summary
    pfam15009
    Location:44 → 337
    TMEM173; Transmembrane protein 173

  4. XM_063811542.1 → XP_063667612.1  stimulator of interferon genes protein isoform X2

    UniProtKB/TrEMBL
    A0A2I3SVT8

  5. XM_016953921.4 → XP_016809410.1  stimulator of interferon genes protein isoform X1

    UniProtKB/TrEMBL
    A0A2J8JIJ5, A0A5S6RD90, H2R3B4
    Conserved Domains (1) summary
    pfam15009
    Location:44 → 337
    TMEM173; Transmembrane protein 173

  6. XM_009449784.5 → XP_009448059.1  stimulator of interferon genes protein isoform X2

    UniProtKB/TrEMBL
    A0A2I3SVT8, A0A2J8JII0
    Related
    ENSPTRP00000080682.1
    Conserved Domains (1) summary
    pfam15009
    Location:44 → 253
    TMEM173; Transmembrane protein 173
Nucleotide Protein
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