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IL6ST interleukin 6 cytokine family signal transducer [ Pan troglodytes (chimpanzee) ]

Gene ID: 461866, updated on 2-Nov-2023

Summary

Official Symbol
IL6STprovided by VGNC
Official Full Name
interleukin 6 cytokine family signal transducerprovided by VGNC
Primary source
VGNC:VGNC:13514
Locus tag
CK820_G0045978
See related
Ensembl:ENSPTRG00000016887
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See IL6ST in Genome Data Viewer
Location:
chromosome: 5
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_04 current NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (59079876..59138002)

Chromosome 5 - NC_072403.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 55 Neighboring gene uncharacterized LOC104006443 Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA U13 Neighboring gene translation initiation factor IF-2-like Neighboring gene interleukin 31 receptor A Neighboring gene heterogeneous nuclear ribonucleoprotein H-like

Genomic regions, transcripts, and products

Genomic Sequence:
NC_072403.1 Chromosome 5 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of tyrosine phosphorylation of STAT protein IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of CRLF-CLCF1 complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
interleukin-6 receptor subunit beta
Names
interleukin 6 signal transducer (gp130, oncostatin M receptor)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

  1. NC_072403.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

    Range
    59079876..59138002
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054685086.1XP_054541061.1  interleukin-6 receptor subunit beta isoform X1

    UniProtKB/TrEMBL
    K7CMK9
  2. XM_001144416.6XP_001144416.2  interleukin-6 receptor subunit beta isoform X1

    UniProtKB/TrEMBL
    K7CMK9
  3. XM_016953299.2XP_016808788.1  interleukin-6 receptor subunit beta isoform X3

    UniProtKB/TrEMBL
    A0A2I3SFX4, A0A2I3SN68, A0A2J8JMU9, A0A2J8JMW6, A0A6D2X3Z6, A0A6D2XHR9
    Related
    ENSPTRP00000078489.1
    Conserved Domains (3) summary
    cd00063
    Location:222321
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam06328
    Location:26112
    Lep_receptor_Ig; Ig-like C2-type domain
    cl21522
    Location:121215
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
  4. XM_054685088.1XP_054541063.1  interleukin-6 receptor subunit beta isoform X4

    UniProtKB/TrEMBL
    A0A2J8JMX3
  5. XM_054685087.1XP_054541062.1  interleukin-6 receptor subunit beta isoform X2