U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

NFKB1 nuclear factor kappa B subunit 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 461406, updated on 18-Aug-2023

Summary

Go to the top of the page Help
Official Symbol
NFKB1provided by VGNC
Official Full Name
nuclear factor kappa B subunit 1provided by VGNC
Primary source
VGNC:VGNC:2972
Locus tag
CK820_G0022237
See related
Ensembl:ENSPTRG00000016320
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See NFKB1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2023_04 current NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 4 NC_072402.1 (103964042..104079607)

Chromosome 4 - NC_072402.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129143752 Neighboring gene zinc finger protein 705A-like Neighboring gene uncharacterized LOC107974357 Neighboring gene mannosidase beta Neighboring gene keratin, type II cytoskeletal 8-like Neighboring gene protein MANBAL-like Neighboring gene ribosome biogenesis protein WDR12-like

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_072402.1 Chromosome 4 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

General protein information

Go to the top of the page Help
Preferred Names
nuclear factor NF-kappa-B p105 subunit
Names
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

  1. NC_072402.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

    Range
    103964042..104079607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016951926.3 → XP_016807415.1  nuclear factor NF-kappa-B p105 subunit isoform X1

    Conserved Domains (7) summary
    cd07935
    Location:51 → 252
    RHD-n_NFkB1; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of kappa B1 (NF-kappa B1)
    cd00204
    Location:585 → 714
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01177
    Location:259 → 360
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    cd08797
    Location:824 → 899
    Death_NFkB1_p105; Death domain of the Nuclear Factor-KappaB1 precursor protein p105
    sd00045
    Location:551 → 588
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:534 → 621
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:694 → 742
    Ank_4; Ankyrin repeats (many copies)

  2. XM_016951927.3 → XP_016807416.1  nuclear factor NF-kappa-B p105 subunit isoform X2

    Conserved Domains (8) summary
    cd07935
    Location:50 → 251
    RHD-n_NFkB1; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of kappa B1 (NF-kappa B1)
    cd00204
    Location:584 → 713
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01177
    Location:258 → 359
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    cd08797
    Location:823 → 898
    Death_NFkB1_p105; Death domain of the Nuclear Factor-KappaB1 precursor protein p105
    pfam12796
    Location:594 → 688
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:551 → 610
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:678 → 734
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:550 → 587
    ANK; ANK repeat [structural motif]

  3. XM_054683229.1 → XP_054539204.1  nuclear factor NF-kappa-B p105 subunit isoform X5

    UniProtKB/TrEMBL
    A0A2J8MAY9

  4. XM_016951929.3 → XP_016807418.1  nuclear factor NF-kappa-B p105 subunit isoform X6

  5. XM_001168718.5 → XP_001168718.1  nuclear factor NF-kappa-B p105 subunit isoform X3

    See identical proteins and their annotated locations for XP_001168718.1

    UniProtKB/TrEMBL
    A0A2J8MAX1, A0A2J8MAY9, A0A6D2W202, H2QPY8
    Related
    ENSPTRP00000028033.2
    Conserved Domains (7) summary
    cd07935
    Location:43 → 244
    RHD-n_NFkB1; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of kappa B1 (NF-kappa B1)
    COG0666
    Location:500 → 706
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd01177
    Location:251 → 352
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    cd08797
    Location:816 → 891
    Death_NFkB1_p105; Death domain of the Nuclear Factor-KappaB1 precursor protein p105
    sd00045
    Location:543 → 580
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:587 → 681
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:690 → 733
    Ank_2; Ankyrin repeats (3 copies)

  6. XM_009448072.4 → XP_009446347.1  nuclear factor NF-kappa-B p105 subunit isoform X4

    See identical proteins and their annotated locations for XP_009446347.1

    UniProtKB/TrEMBL
    A0A2J8MAX5, A0A2J8MAY9, A0A803KIE4, K7DQM6
    Conserved Domains (7) summary
    cd07935
    Location:42 → 243
    RHD-n_NFkB1; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of kappa B1 (NF-kappa B1)
    COG0666
    Location:499 → 705
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd01177
    Location:250 → 351
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    cd08797
    Location:815 → 890
    Death_NFkB1_p105; Death domain of the Nuclear Factor-KappaB1 precursor protein p105
    sd00045
    Location:542 → 579
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:586 → 680
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:689 → 732
    Ank_2; Ankyrin repeats (3 copies)

  7. XM_016951931.3 → XP_016807420.1  nuclear factor NF-kappa-B p105 subunit isoform X7

    UniProtKB/TrEMBL
    A0A2J8MAY9
    Conserved Domains (8) summary
    cd00204
    Location:445 → 574
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01177
    Location:119 → 220
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    cd08797
    Location:684 → 759
    Death_NFkB1_p105; Death domain of the Nuclear Factor-KappaB1 precursor protein p105
    pfam12796
    Location:455 → 549
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:412 → 471
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:539 → 595
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:411 → 448
    ANK; ANK repeat [structural motif]
    cl08275
    Location:1 → 112
    RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous