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MYBPC1 myosin binding protein C, slow type [ Homo sapiens (human) ]

Gene ID: 4604, updated on 8-Dec-2018

Summary

Official Symbol
MYBPC1provided by HGNC
Official Full Name
myosin binding protein C, slow typeprovided by HGNC
Primary source
HGNC:HGNC:7549
See related
Ensembl:ENSG00000196091 MIM:160794
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LCCS4; MYBPCC; MYBPCS
Summary
This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Expression
Biased expression in prostate (RPKM 75.7), esophagus (RPKM 49.2) and 1 other tissue See more
Orthologs

Genomic context

See MYBPC1 in Genome Data Viewer
Location:
12q23.2
Exon count:
34
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 12 NC_000012.12 (101594849..101695841)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (101988709..102079658)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene Spi-C transcription factor Neighboring gene uncharacterized LOC105369935 Neighboring gene uncharacterized LOC105369938 Neighboring gene uncharacterized LOC105369937 Neighboring gene choline phosphotransferase 1 Neighboring gene RNY1 pseudogene 16 Neighboring gene synaptonemal complex protein 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Distal arthrogryposis type 1B
MedGen: C3280526 OMIM: 614335 GeneReviews: Not available
Compare labs
Lethal congenital contracture syndrome 4
MedGen: C3554046 OMIM: 614915 GeneReviews: Not available
Compare labs

NHGRI GWAS Catalog

Description
Gene network analysis in a pediatric cohort identifies novel lung function genes.
NHGRI GWA Catalog

Pathways from BioSystems

  • Muscle contraction, organism-specific biosystem (from REACTOME)
    Muscle contraction, organism-specific biosystemIn this module, the processes by which calcium binding triggers actin - myosin interactions and force generation in smooth and striated muscle tissues are annotated.
  • Striated Muscle Contraction, organism-specific biosystem (from REACTOME)
    Striated Muscle Contraction, organism-specific biosystemStriated muscle contraction is a process whereby force is generated within striated muscle tissue, resulting in a change in muscle geometry, or in short, increased force being exerted on the tendons....
  • Striated Muscle Contraction, organism-specific biosystem (from WikiPathways)
    Striated Muscle Contraction, organism-specific biosystemMuscle contraction is the process where muscle tissue is activated by a signal from the nervous system. In case of voluntary action the nervous signals are initiated from the brain by so called actio...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
muscle alpha-actinin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
structural constituent of muscle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
titin binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
cardiac muscle fiber development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cardiac muscle tissue morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cardiac myofibril assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
muscle contraction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
muscle filament sliding TAS
Traceable Author Statement
more info
 
sarcomere organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
skeletal muscle myosin thick filament assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
skeletal muscle thin filament assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
striated muscle myosin thick filament assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
M band IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Z disc IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
myofibril ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
myosin filament IEA
Inferred from Electronic Annotation
more info
 
sarcomere IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
striated muscle thin filament IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
myosin-binding protein C, slow-type
Names
C-protein, skeletal muscle slow isoform
skeletal muscle C-protein
slow MyBP-C

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_031912.1 RefSeqGene

    Range
    5001..95950
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001254718.1NP_001241647.1  myosin-binding protein C, slow-type isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) lacks three exons and includes an alternate exon in the coding region, compared to variant 1. The encoded isoform (5) is longer and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK295727, AK296681, AL832456, BC030980, BP232990, BX500247
    Consensus CDS
    CCDS58268.1
    UniProtKB/Swiss-Prot
    Q00872
    UniProtKB/TrEMBL
    Q86TA8
    Related
    ENSP00000400908.2, ENST00000452455.6
    Conserved Domains (7) summary
    cd00096
    Location:10641129
    Ig; Immunoglobulin domain
    cd05894
    Location:531616
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:356414
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:534616
    IG_like; Immunoglobulin like
    cd00063
    Location:620710
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10471136
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:857928
    Ig; Immunoglobulin domain
  2. NM_001254719.1NP_001241648.1  myosin-binding protein C, slow-type isoform 6

    See identical proteins and their annotated locations for NP_001241648.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks two consecutive exons in the 5' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (6) is shorter than isoform 1.
    Source sequence(s)
    AK295727, AL832456, BC030980, BC143503, BX500247, CD614901, DA433791
    Consensus CDS
    CCDS58269.1
    UniProtKB/Swiss-Prot
    Q00872
    UniProtKB/TrEMBL
    Q86TA8
    Related
    ENSP00000440034.2, ENST00000545503.6
    Conserved Domains (7) summary
    cd00096
    Location:10461111
    Ig; Immunoglobulin domain
    cd05894
    Location:531616
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:356414
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:534616
    IG_like; Immunoglobulin like
    cd00063
    Location:620710
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10291118
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:839910
    Ig; Immunoglobulin domain
  3. NM_001254720.1NP_001241649.1  myosin-binding protein C, slow-type isoform 7

    See identical proteins and their annotated locations for NP_001241649.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) lacks three exons in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (7) is shorter than isoform 1.
    Source sequence(s)
    AK295727, AL832456, BC030980, BC143504, BX500247, CD614901, DA433791
    Consensus CDS
    CCDS58271.1
    UniProtKB/Swiss-Prot
    Q00872
    UniProtKB/TrEMBL
    Q86TA8
    Related
    ENSP00000442847.1, ENST00000541119.5
    Conserved Domains (7) summary
    cd00096
    Location:10341099
    Ig; Immunoglobulin domain
    cd05894
    Location:519604
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:344402
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:522604
    IG_like; Immunoglobulin like
    cd00063
    Location:608698
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10171106
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:827898
    Ig; Immunoglobulin domain
  4. NM_001254721.1NP_001241650.1  myosin-binding protein C, slow-type isoform 8

    See identical proteins and their annotated locations for NP_001241650.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) lacks three exons in the 5' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (8) is shorter than isoform 1.
    Source sequence(s)
    AK295727, AL832456, BC030980, BC143495, BX500247, DA433791
    Consensus CDS
    CCDS58270.1
    UniProtKB/Swiss-Prot
    Q00872
    UniProtKB/TrEMBL
    Q86TA8
    Related
    ENSP00000446128.1, ENST00000536007.5
    Conserved Domains (7) summary
    cd00096
    Location:10271092
    Ig; Immunoglobulin domain
    cd05894
    Location:512597
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:337395
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:515597
    IG_like; Immunoglobulin like
    cd00063
    Location:601691
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10101099
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:820891
    Ig; Immunoglobulin domain
  5. NM_001254722.1NP_001241651.1  myosin-binding protein C, slow-type isoform 9

    See identical proteins and their annotated locations for NP_001241651.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) lacks four consecutive exons in the 5' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (9) is shorter than isoform 1.
    Source sequence(s)
    AK295727, AK296681, AL832456, BC030980, BX500247
    Consensus CDS
    CCDS58273.1
    UniProtKB/Swiss-Prot
    Q00872
    UniProtKB/TrEMBL
    Q86TA8
    Related
    ENSP00000448175.1, ENST00000547405.5
    Conserved Domains (7) summary
    cd00096
    Location:10201085
    Ig; Immunoglobulin domain
    cd05894
    Location:505590
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:330388
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:508590
    IG_like; Immunoglobulin like
    cd00063
    Location:594684
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10031092
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:813884
    Ig; Immunoglobulin domain
  6. NM_001254723.1NP_001241652.1  myosin-binding protein C, slow-type isoform 10

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) lacks five exons in the coding region, compared to variant 1. The encoded isoform (10) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK056587, AK295727, AK303401, AL832456, BC030980, BX500247
    Consensus CDS
    CCDS58272.1
    UniProtKB/Swiss-Prot
    Q00872
    UniProtKB/TrEMBL
    B3KPP3, Q86TA8
    Related
    ENSP00000376665.3, ENST00000392934.7
    Conserved Domains (7) summary
    cd00096
    Location:10331098
    Ig; Immunoglobulin domain
    cd05894
    Location:518603
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:343401
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:521603
    IG_like; Immunoglobulin like
    cd00063
    Location:607697
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10161105
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:826897
    Ig; Immunoglobulin domain
  7. NM_002465.3NP_002456.2  myosin-binding protein C, slow-type isoform 1

    See identical proteins and their annotated locations for NP_002456.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1.
    Source sequence(s)
    AK295727, AL831993, AL832456, BC030980, BX500247, DA433791
    Consensus CDS
    CCDS9083.1
    UniProtKB/Swiss-Prot
    Q00872
    UniProtKB/TrEMBL
    Q86TA8
    Related
    ENSP00000354849.2, ENST00000361466.6
    Conserved Domains (7) summary
    cd00096
    Location:10711136
    Ig; Immunoglobulin domain
    cd05894
    Location:556641
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:381439
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:559641
    IG_like; Immunoglobulin like
    cd00063
    Location:645735
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10541143
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:864935
    Ig; Immunoglobulin domain
  8. NM_206819.2NP_996555.1  myosin-binding protein C, slow-type isoform 2

    See identical proteins and their annotated locations for NP_996555.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 3' coding region, which results in a frameshift, compared to variant 1. the encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK292976, AK295727, AL832456, BC030980, BX500247
    Consensus CDS
    CCDS9084.1
    UniProtKB/Swiss-Prot
    Q00872
    UniProtKB/TrEMBL
    A8KAB1, Q86TA8
    Related
    ENSP00000354845.2, ENST00000361685.6
    Conserved Domains (7) summary
    cd00096
    Location:10711136
    Ig; Immunoglobulin domain
    cd05894
    Location:556641
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:381439
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:559641
    IG_like; Immunoglobulin like
    cd00063
    Location:645735
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10541143
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:864935
    Ig; Immunoglobulin domain
  9. NM_206820.2NP_996556.1  myosin-binding protein C, slow-type isoform 3

    See identical proteins and their annotated locations for NP_996556.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks three exons and includes an alternate exon in the coding region, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK292976, AK295727, AK296681, AL832456, BC030980, BX500247, DA433791, X66276
    Consensus CDS
    CCDS9085.1
    UniProtKB/Swiss-Prot
    Q00872
    UniProtKB/TrEMBL
    A8KAB1, Q86TA8
    Related
    ENSP00000449702.1, ENST00000550270.1
    Conserved Domains (7) summary
    cd00096
    Location:10641129
    Ig; Immunoglobulin domain
    cd05894
    Location:531616
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:356414
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:534616
    IG_like; Immunoglobulin like
    cd00063
    Location:620710
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10471136
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:857928
    Ig; Immunoglobulin domain
  10. NM_206821.2NP_996557.1  myosin-binding protein C, slow-type isoform 4

    See identical proteins and their annotated locations for NP_996557.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks three exons in the coding region compared to variant 1. The encoded isoform (4) is shorter and has a distinct C-terminus, compared to variant 1.
    Source sequence(s)
    AK295727, AL832456, BC030980, BX500247, DA433791, X73114
    Consensus CDS
    CCDS55877.1
    UniProtKB/Swiss-Prot
    Q00872
    UniProtKB/TrEMBL
    Q86TA8
    Related
    ENSP00000447900.1, ENST00000553190.5
    Conserved Domains (7) summary
    cd00096
    Location:10461111
    Ig; Immunoglobulin domain
    cd05894
    Location:531616
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:356414
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:534616
    IG_like; Immunoglobulin like
    cd00063
    Location:620710
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10291118
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:839910
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p12 Primary Assembly

    Range
    101594849..101695841
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017019320.1XP_016874809.1  myosin-binding protein C, slow-type isoform X14

  2. XM_017019322.1XP_016874811.1  myosin-binding protein C, slow-type isoform X16

  3. XM_006719407.3XP_006719470.1  myosin-binding protein C, slow-type isoform X3

    Conserved Domains (7) summary
    cd00096
    Location:10771142
    Ig; Immunoglobulin domain
    cd05894
    Location:544629
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:369427
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:547629
    IG_like; Immunoglobulin like
    cd00063
    Location:633723
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10601149
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:870941
    Ig; Immunoglobulin domain
  4. XM_005268876.4XP_005268933.1  myosin-binding protein C, slow-type isoform X9

    Conserved Domains (7) summary
    cd00096
    Location:10591124
    Ig; Immunoglobulin domain
    cd05894
    Location:544629
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:369427
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:547629
    IG_like; Immunoglobulin like
    cd00063
    Location:633723
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10421131
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:852923
    Ig; Immunoglobulin domain
  5. XM_006719411.3XP_006719474.1  myosin-binding protein C, slow-type isoform X10

    See identical proteins and their annotated locations for XP_006719474.1

    Conserved Domains (7) summary
    cd00096
    Location:10641129
    Ig; Immunoglobulin domain
    cd05894
    Location:531616
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:356414
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:534616
    IG_like; Immunoglobulin like
    cd00063
    Location:620710
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10471136
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:857928
    Ig; Immunoglobulin domain
  6. XM_006719409.3XP_006719472.1  myosin-binding protein C, slow-type isoform X7

    Conserved Domains (7) summary
    cd00096
    Location:10641129
    Ig; Immunoglobulin domain
    cd05894
    Location:531616
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:356414
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:534616
    IG_like; Immunoglobulin like
    cd00063
    Location:620710
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10471136
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:857928
    Ig; Immunoglobulin domain
  7. XM_017019317.1XP_016874806.1  myosin-binding protein C, slow-type isoform X11

  8. XM_017019316.2XP_016874805.1  myosin-binding protein C, slow-type isoform X6

  9. XM_006719406.4XP_006719469.1  myosin-binding protein C, slow-type isoform X2

    Conserved Domains (7) summary
    cd00096
    Location:10891154
    Ig; Immunoglobulin domain
    cd05894
    Location:556641
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:381439
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:559641
    IG_like; Immunoglobulin like
    cd00063
    Location:645735
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10721161
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:882953
    Ig; Immunoglobulin domain
  10. XM_006719405.4XP_006719468.1  myosin-binding protein C, slow-type isoform X1

    Conserved Domains (7) summary
    cd00096
    Location:10891154
    Ig; Immunoglobulin domain
    cd05894
    Location:556641
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:381439
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:559641
    IG_like; Immunoglobulin like
    cd00063
    Location:645735
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10721161
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:882953
    Ig; Immunoglobulin domain
  11. XM_017019315.2XP_016874804.1  myosin-binding protein C, slow-type isoform X5

  12. XM_017019319.2XP_016874808.1  myosin-binding protein C, slow-type isoform X13

  13. XM_006719410.4XP_006719473.1  myosin-binding protein C, slow-type isoform X8

    Related
    ENSP00000447660.1, ENST00000549145.5
    Conserved Domains (7) summary
    cd00096
    Location:10891154
    Ig; Immunoglobulin domain
    cd05894
    Location:556641
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:381439
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:559641
    IG_like; Immunoglobulin like
    cd00063
    Location:645735
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10721161
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:882953
    Ig; Immunoglobulin domain
  14. XM_006719408.4XP_006719471.1  myosin-binding protein C, slow-type isoform X4

    Conserved Domains (7) summary
    cd00096
    Location:10711136
    Ig; Immunoglobulin domain
    cd05894
    Location:556641
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00408
    Location:381439
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:559641
    IG_like; Immunoglobulin like
    cd00063
    Location:645735
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:10541143
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:864935
    Ig; Immunoglobulin domain
  15. XM_017019321.2XP_016874810.1  myosin-binding protein C, slow-type isoform X15

  16. XM_017019318.2XP_016874807.1  myosin-binding protein C, slow-type isoform X12

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