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SCN10A sodium voltage-gated channel alpha subunit 10 [ Pan troglodytes (chimpanzee) ]

Gene ID: 460274, updated on 29-Mar-2024

Summary

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Official Symbol
SCN10Aprovided by VGNC
Official Full Name
sodium voltage-gated channel alpha subunit 10provided by VGNC
Primary source
VGNC:VGNC:12180
Locus tag
CK820_G0009099
See related
Ensembl:ENSPTRG00000014763
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See SCN10A in Genome Data Viewer
Location:
chromosome: 3
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 2 NC_086015.1 (42699814..42796380, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 3 NC_072401.1 (42699478..42796044, complement)

Chromosome 2 - NC_086015.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein eL20-like Neighboring gene sodium voltage-gated channel alpha subunit 5 Neighboring gene histone-lysine N-methyltransferase SETMAR-like Neighboring gene sodium voltage-gated channel alpha subunit 11 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables voltage-gated sodium channel activity involved in cardiac muscle cell action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane depolarization during action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuronal action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of atrial cardiac muscle cell membrane depolarization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of heart rate IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of voltage-gated sodium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sodium channel protein type 10 subunit alpha
Names
sodium channel, voltage-gated, type X, alpha subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    42699814..42796380 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009445192.3 → XP_009443467.1  sodium channel protein type 10 subunit alpha isoform X3

    UniProtKB/TrEMBL
    H2R1N2
    Conserved Domains (4) summary
    cd13433
    Location:1324 → 1376
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1074 → 1332
    Ion_trans; Ion transport protein
    pfam06512
    Location:809 → 1052
    Na_trans_assoc; Sodium ion transport-associated
    pfam16905
    Location:1647 → 1704
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  2. XM_009445191.3 → XP_009443466.1  sodium channel protein type 10 subunit alpha isoform X2

    UniProtKB/TrEMBL
    H2R1N2
    Conserved Domains (5) summary
    cd13433
    Location:1421 → 1473
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1171 → 1429
    Ion_trans; Ion transport protein
    pfam06512
    Location:907 → 1149
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:466 → 537
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1744 → 1801
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  3. XM_009445190.3 → XP_009443465.1  sodium channel protein type 10 subunit alpha isoform X1

    UniProtKB/TrEMBL
    H2R1N2
    Related
    ENSPTRP00000042609.3
    Conserved Domains (5) summary
    cd13433
    Location:1422 → 1474
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1172 → 1430
    Ion_trans; Ion transport protein
    pfam06512
    Location:907 → 1150
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:466 → 537
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1745 → 1802
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
Nucleotide Protein
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