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ITGAV integrin subunit alpha V [ Pan troglodytes (chimpanzee) ]

Gene ID: 459807, updated on 3-Dec-2024

Summary

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Official Symbol
ITGAVprovided by VGNC
Official Full Name
integrin subunit alpha Vprovided by VGNC
Primary source
VGNC:VGNC:2706
Locus tag
CK820_G0001708
See related
Ensembl:ENSPTRG00000012719
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See ITGAV in Genome Data Viewer
Location:
chromosome: 13
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (88628555..88721660)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (88630174..88721623)

Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH-type containing 15 Neighboring gene endogenous retrovirus group K member 19 Rec protein Neighboring gene family with sequence similarity 171 member B Neighboring gene zinc finger SWIM-type containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin alpha-V
Names
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    88628555..88721660
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_515967.8 → XP_515967.3  integrin alpha-V isoform X1

    See identical proteins and their annotated locations for XP_515967.3

    UniProtKB/TrEMBL
    A0A2I3TQP4, A0A2J8PRS4, A0A2J8PRT3, A0A6D2WEZ7, A0A6D2XWV7, H2R6C3
    Related
    ENSPTRP00000048970.4
    Conserved Domains (4) summary
    smart00191
    Location:367 → 421
    Int_alpha; Integrin alpha (beta-propellor repeats)
    sd00039
    Location:51 → 120
    7WD40; WD40 repeat [structural motif]
    pfam08441
    Location:467 → 914
    Integrin_alpha2; Integrin alpha
    pfam13517
    Location:221 → 271
    VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

  2. XM_054679966.2 → XP_054535941.1  integrin alpha-V isoform X2

    UniProtKB/TrEMBL
    A0A2I3SM65

  3. XM_063791326.1 → XP_063647396.1  integrin alpha-V isoform X4

    UniProtKB/TrEMBL
    A0A2I3S4U1

  4. XM_063791325.1 → XP_063647395.1  integrin alpha-V isoform X3

    UniProtKB/TrEMBL
    A0A2I3S4U1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials