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NCOA1 nuclear receptor coactivator 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 459068, updated on 2-Nov-2023

Summary

Official Symbol
NCOA1provided by VGNC
Official Full Name
nuclear receptor coactivator 1provided by VGNC
Primary source
VGNC:VGNC:310
Locus tag
CK820_G0009611
See related
Ensembl:ENSPTRG00000011715
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See NCOA1 in Genome Data Viewer
Location:
chromosome: 2A
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2023_04 current NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2A NC_072399.1 (24472245..24751115)

Chromosome 2A - NC_072399.1Genomic Context describing neighboring genes Neighboring gene intersectin 2 Neighboring gene non-histone chromosomal protein HMG-17-like Neighboring gene 60S ribosomal protein L36a-like Neighboring gene U6 spliceosomal RNA Neighboring gene peptidyl-tRNA hydrolase domain containing 1 Neighboring gene centromere protein O Neighboring gene adenylate cyclase 3

Genomic regions, transcripts, and products

Genomic Sequence:
NC_072399.1 Chromosome 2A Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables nuclear receptor coactivator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to hormone stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
nuclear receptor coactivator 1
XP_009440408.1
XP_016803637.1
XP_054533700.1
XP_054533701.1
XP_054533702.1
XP_054533703.1
XP_054533704.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

  1. NC_072399.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

    Range
    24472245..24751115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016948148.3XP_016803637.1  nuclear receptor coactivator 1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8NLC4, A0A2J8NLF0, A0A6D2YCQ2, H2QHJ2
    Conserved Domains (9) summary
    PHA03247
    Location:9741309
    PHA03247; large tegument protein UL36; Provisional
    cd00130
    Location:120213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    cd18948
    Location:2787
    bHLH-PAS_NCoA1_SRC1; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 1 (NCoA-1) and similar proteins
    pfam07469
    Location:12121268
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:924969
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:632708
    SRC-1; Steroid receptor coactivator
    pfam14598
    Location:260370
    PAS_11; PAS domain
    pfam16279
    Location:741818
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:468590
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein
  2. XM_054677726.1XP_054533701.1  nuclear receptor coactivator 1 isoform X3

    UniProtKB/TrEMBL
    A0A2J8NLF0
  3. XM_054677728.1XP_054533703.1  nuclear receptor coactivator 1 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SMH0, A0A2J8NLC3, A0A2J8NLF0, A0A6D2Y8C8
  4. XM_009442133.3XP_009440408.1  nuclear receptor coactivator 1 isoform X2

    See identical proteins and their annotated locations for XP_009440408.1

    UniProtKB/TrEMBL
    A0A2J8NLB6, A0A2J8NLF0
    Conserved Domains (9) summary
    PHA03247
    Location:9741309
    PHA03247; large tegument protein UL36; Provisional
    cd00130
    Location:120213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    cd18948
    Location:2787
    bHLH-PAS_NCoA1_SRC1; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in nuclear receptor coactivator 1 (NCoA-1) and similar proteins
    pfam07469
    Location:12121268
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:924969
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:632708
    SRC-1; Steroid receptor coactivator
    pfam14598
    Location:260370
    PAS_11; PAS domain
    pfam16279
    Location:741818
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:468590
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein
  5. XM_054677725.1XP_054533700.1  nuclear receptor coactivator 1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8NLC4, A0A2J8NLF0, A0A6D2YCQ2, H2QHJ2
  6. XM_054677727.1XP_054533702.1  nuclear receptor coactivator 1 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SMH0, A0A2J8NLC3, A0A2J8NLF0, A0A6D2Y8C8
  7. XM_054677729.1XP_054533704.1  nuclear receptor coactivator 1 isoform X5

    UniProtKB/TrEMBL
    A0A2J8NLA9