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PPARA peroxisome proliferator activated receptor alpha [ Pan troglodytes (chimpanzee) ]

Gene ID: 458910, updated on 17-Aug-2024

Summary

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Official Symbol
PPARAprovided by VGNC
Official Full Name
peroxisome proliferator activated receptor alphaprovided by VGNC
Primary source
VGNC:VGNC:12916
See related
Ensembl:ENSPTRG00000014505
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See PPARA in Genome Data Viewer
Location:
chromosome: 23
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 23 NC_086016.1 (48146713..48227984)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 22 NC_072420.1 (41179047..41268157)

Chromosome 23 - NC_086016.1Genomic Context describing neighboring genes Neighboring gene microRNA let-7a-3 Neighboring gene microRNA let-7b Neighboring gene cysteine rich DPF motif domain containing 1 Neighboring gene polycystin family receptor for egg jelly

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hormone-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cholesterol storage IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peroxisome proliferator-activated receptor alpha
Names
peroxisome proliferative activated receptor, alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086016.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    48146713..48227984
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009438608.5 → XP_009436883.1  peroxisome proliferator-activated receptor alpha isoform X1

    See identical proteins and their annotated locations for XP_009436883.1

    UniProtKB/TrEMBL
    H2QLW3
    Conserved Domains (2) summary
    cd06932
    Location:201 → 466
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:101 → 184
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

  2. XM_001136470.8 → XP_001136470.1  peroxisome proliferator-activated receptor alpha isoform X1

    See identical proteins and their annotated locations for XP_001136470.1

    UniProtKB/TrEMBL
    H2QLW3
    Conserved Domains (2) summary
    cd06932
    Location:201 → 466
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:101 → 184
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

  3. XM_009438609.5 → XP_009436884.1  peroxisome proliferator-activated receptor alpha isoform X1

    See identical proteins and their annotated locations for XP_009436884.1

    UniProtKB/TrEMBL
    H2QLW3
    Conserved Domains (2) summary
    cd06932
    Location:201 → 466
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:101 → 184
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

  4. XM_063808094.1 → XP_063664164.1  peroxisome proliferator-activated receptor alpha isoform X1

    UniProtKB/TrEMBL
    H2QLW3

  5. XM_024352771.3 → XP_024208539.1  peroxisome proliferator-activated receptor alpha isoform X1

    UniProtKB/TrEMBL
    H2QLW3
    Conserved Domains (2) summary
    cd06932
    Location:201 → 466
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:101 → 184
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

  6. XM_063808095.1 → XP_063664165.1  peroxisome proliferator-activated receptor alpha isoform X1

    UniProtKB/TrEMBL
    H2QLW3

  7. XM_063808096.1 → XP_063664166.1  peroxisome proliferator-activated receptor alpha isoform X2

Nucleotide Protein
Heading Accession and Version

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