PPARA peroxisome proliferator activated receptor alpha [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PPARAprovided by VGNC
Official Full Name: peroxisome proliferator activated receptor alphaprovided by VGNC
Primary source: VGNC:VGNC:12916
See related: Ensembl:ENSPTRG00000014505
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2023_04	current	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	22	NC_072420.1 (41179047..41268157)

Chromosome 22 - NC_072420.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_072420.1 Chromosome 22 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

A009O07 (e-PCR)
- UniSTS:20995

RH27889 (e-PCR)
- UniSTS:87061

G32699 (e-PCR)
- UniSTS:117281

SHGC-32144 (e-PCR)
- UniSTS:80933

D8S2279 (e-PCR)
- UniSTS:473907

D22S1586 (e-PCR)
- UniSTS:473697

D12S1332 (e-PCR)
- UniSTS:48481

PPARA_2988 (e-PCR)
- UniSTS:462440

Cda02e06 (e-PCR)
- UniSTS:91036

RH45682 (e-PCR)
- UniSTS:34755

WI-17171 (e-PCR)
- UniSTS:57045

D22S1562 (e-PCR)
- UniSTS:8927

G20431 (e-PCR)
- UniSTS:20447

A005R09 (e-PCR)
- UniSTS:20448

D15S1390 (e-PCR)
- UniSTS:474340

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables nuclear receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in hormone-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of lipid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: peroxisome proliferator-activated receptor alpha

Names: peroxisome proliferative activated receptor, alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

NC_072420.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Range

41179047..41268157

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009438608.4 → XP_009436883.1 peroxisome proliferator-activated receptor alpha

See identical proteins and their annotated locations for XP_009436883.1

UniProtKB/TrEMBL

H2QLW3

Conserved Domains (2) summary

cd06932
Location:201 → 466

NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors

cd06965
Location:101 → 184

NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
XM_001136470.7 → XP_001136470.1 peroxisome proliferator-activated receptor alpha

See identical proteins and their annotated locations for XP_001136470.1

UniProtKB/TrEMBL

H2QLW3

Conserved Domains (2) summary

cd06932
Location:201 → 466

NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors

cd06965
Location:101 → 184

NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
XM_009438609.4 → XP_009436884.1 peroxisome proliferator-activated receptor alpha

See identical proteins and their annotated locations for XP_009436884.1

UniProtKB/TrEMBL

H2QLW3

Conserved Domains (2) summary

cd06932
Location:201 → 466

NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors

cd06965
Location:101 → 184

NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
XM_016939396.3 → XP_016794885.1 peroxisome proliferator-activated receptor alpha

UniProtKB/TrEMBL

H2QLW3

Related

ENSPTRP00000025003.5

Conserved Domains (2) summary

cd06932
Location:201 → 466

NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors

cd06965
Location:101 → 184

NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
XM_024352771.2 → XP_024208539.1 peroxisome proliferator-activated receptor alpha

UniProtKB/TrEMBL

H2QLW3

Conserved Domains (2) summary

cd06932
Location:201 → 466

NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors

cd06965
Location:101 → 184

NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers