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PDGFB platelet derived growth factor subunit B [ Pan troglodytes (chimpanzee) ]

Gene ID: 458844, updated on 3-Dec-2024

Summary

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Official Symbol
PDGFBprovided by VGNC
Official Full Name
platelet derived growth factor subunit Bprovided by VGNC
Primary source
VGNC:VGNC:6704
Locus tag
CK820_G0027598
See related
Ensembl:ENSPTRG00000014392
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See PDGFB in Genome Data Viewer
Location:
chromosome: 23
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 23 NC_086016.1 (41179258..41241979, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 22 NC_072420.1 (34211653..34274474, complement)

Chromosome 23 - NC_086016.1Genomic Context describing neighboring genes Neighboring gene apolipoprotein B mRNA editing enzyme catalytic subunit 3H Neighboring gene uncharacterized LOC129138513 Neighboring gene chromobox 7 Neighboring gene uncharacterized LOC129138512 Neighboring gene uncharacterized LOC134809675

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables platelet-derived growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in platelet-derived growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAP kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
platelet-derived growth factor subunit B
Names
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086016.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    41179258..41241979 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_515140.7 → XP_515140.3  platelet-derived growth factor subunit B isoform X1

    UniProtKB/TrEMBL
    A0A2I3TIH9, A0A2J8LNJ9, A0A6D2Y4M1

  2. XM_063808240.1 → XP_063664310.1  platelet-derived growth factor subunit B isoform X2

    UniProtKB/TrEMBL
    A0A2I3TIH9, A0A2J8LNJ9, A0A6D2Y4M1

  3. XM_009438423.5 → XP_009436698.2  platelet-derived growth factor subunit B isoform X2

    UniProtKB/TrEMBL
    A0A2I3TIH9, A0A2J8LNJ9, A0A6D2Y4M1

  4. XM_016939194.3 → XP_016794683.1  platelet-derived growth factor subunit B isoform X3

RNA

  1. XR_008541827.2 RNA Sequence

  2. XR_001712712.4 RNA Sequence

  3. XR_001712713.4 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials