U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MAPK1 mitogen-activated protein kinase 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 458680, updated on 12-Apr-2023

Summary

Go to the top of the page Help
Official Symbol
MAPK1provided by VGNC
Official Full Name
mitogen-activated protein kinase 1provided by VGNC
Primary source
VGNC:VGNC:12896
Locus tag
CK820_G0053002
See related
Ensembl:ENSPTRG00000014120
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MAPK1 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_04 current NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 22 NC_072420.1 (16746369..16851289, complement)

Chromosome 22 - NC_072420.1Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase like 2 Neighboring gene uncharacterized LOC129138541 Neighboring gene yippee like 1 Neighboring gene uncharacterized LOC129138540 Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1F Neighboring gene DNA topoisomerase III beta

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_072420.1 Chromosome 22 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Prostaglandin E2 induces cyclooxygenase-2 expression in human non-pigmented ciliary epithelial cells through activation of p38 and p42/44 mitogen-activated protein kinases. Rösch S, et al. Biochem Biophys Res Commun, 2005 Dec 16. PMID 16256948

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Collectively, our results demonstrate that PGE(2) at physiologically relevant concentrations induces COX-2 expression in human NPE cells via activation of EP(2)- and EP(4) receptors and phosphorylation of p38 and p42/44 MAPKs.
    Title: Prostaglandin E2 induces cyclooxygenase-2 expression in human non-pigmented ciliary epithelial cells through activation of p38 and p42/44 mitogen-activated protein kinases.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

General protein information

Go to the top of the page Help
Preferred Names
mitogen-activated protein kinase 1
XP_003317171.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

  1. NC_072420.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

    Range
    16746369..16851289 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003317123.6 → XP_003317171.1  mitogen-activated protein kinase 1

    See identical proteins and their annotated locations for XP_003317171.1

    UniProtKB/TrEMBL
    A0A2J8IUI8, A0A6D2YB98, H2QLB4
    Related
    ENSPTRP00000024313.4
    Conserved Domains (1) summary
    cd07849
    Location:19 → 353
    STKc_ERK1_2_like; Catalytic domain of Extracellular signal-Regulated Kinase 1 and 2-like Serine/Threonine Kinases
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous