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PTGIS prostaglandin I2 synthase [ Pan troglodytes (chimpanzee) ]

Gene ID: 458323, updated on 2-Nov-2023

Summary

Official Symbol
PTGISprovided by VGNC
Official Full Name
prostaglandin I2 synthaseprovided by VGNC
Primary source
VGNC:VGNC:14478
Locus tag
CK820_G0019886
See related
Ensembl:ENSPTRG00000013608
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See PTGIS in Genome Data Viewer
Location:
chromosome: 20
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_04 current NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 20 NC_072418.1 (55834450..55898839, complement)

Chromosome 20 - NC_072418.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104003633 Neighboring gene small nucleolar SNORD12/SNORD106 Neighboring gene uncharacterized LOC104003634 Neighboring gene potassium voltage-gated channel subfamily B member 1 Neighboring gene uncharacterized LOC107970052 Neighboring gene beta-1,4-galactosyltransferase 5 Neighboring gene small nuclear ribonucleoprotein F-like

Genomic regions, transcripts, and products

Genomic Sequence:
NC_072418.1 Chromosome 20 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
PubMed 
enables prostaglandin-I synthase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in prostaglandin biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
prostacyclin synthase
Names
prostaglandin I2 (prostacyclin) synthase
XP_016793607.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

  1. NC_072418.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

    Range
    55834450..55898839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016938118.3XP_016793607.1  prostacyclin synthase

    UniProtKB/TrEMBL
    A0A2I3SKA0, A0A2J8MJF5, A0A6D2WN01, K7C397
    Related
    ENSPTRP00000085301.1
    Conserved Domains (1) summary
    cl12078
    Location:27494
    p450; Cytochrome P450