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GlnRS Glutaminyl-tRNA synthetase [ Drosophila melanogaster (fruit fly) ]

Gene ID: 45786, updated on 10-Jan-2019

Summary

Official Symbol
GlnRSprovided by FlyBase
Official Full Name
Glutaminyl-tRNA synthetaseprovided by FlyBase
Primary source
FLYBASE:FBgn0027090
Locus tag
Dmel_CG10506
Gene type
protein coding
RNA name
Glutaminyl-tRNA synthetase
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Aast-g1n; Aats-gln; BcDNA:GH11673; CG10506; Dmel\CG10506; l(3)05461; qars; QRS

Genomic context

See GlnRS in Genome Data Viewer
Location:
96C8-96C8; 3-87 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.18 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25263267..25265721, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21088989..21091443, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene RIO kinase 2 Neighboring gene ncRNA Neighboring gene pseudo

Genomic regions, transcripts, and products

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the GlnRS gene: The GlnRS gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
glutamine-tRNA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glutamine-tRNA ligase activity TAS
Traceable Author Statement
more info
PubMed 
protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein kinase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
dendrite morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
glutaminyl-tRNA aminoacylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glutaminyl-tRNA aminoacylation TAS
Traceable Author Statement
more info
PubMed 
negative regulation of stress-activated MAPK cascade IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
aminoacyl-tRNA synthetase multienzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
aminoacyl-tRNA synthetase multienzyme complex IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm TAS
Traceable Author Statement
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
Glutaminyl-tRNA synthetase
Names
CG10506-PA
GlnRS-PA
NP_524841.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    25263267..25265721 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080102.5NP_524841.1  Glutaminyl-tRNA synthetase [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524841.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9Y105
    Related
    FBpp0084240, FBtr0084866
    Conserved Domains (5) summary
    PLN02859
    Location:10777
    PLN02859; glutamine-tRNA ligase
    cd00807
    Location:266570
    GlnRS_core; catalytic core domain of glutaminyl-tRNA synthetase
    pfam03950
    Location:568755
    tRNA-synt_1c_C; tRNA synthetases class I (E and Q), anti-codon binding domain
    pfam04557
    Location:168259
    tRNA_synt_1c_R2; Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
    pfam04558
    Location:10165
    tRNA_synt_1c_R1; Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1
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