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PSEN2 presenilin 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 457790, updated on 8-Nov-2017
Official Symbol
PSEN2provided by VGNC
Official Full Name
presenilin 2provided by VGNC
Primary source
VGNC:VGNC:1474
See related
Ensembl:ENSPTRG00000002052
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
104 current Pan_tro 3.0 (GCF_000001515.7) 1 NC_006468.4 (205919664..205945445)
103 previous assembly Pan_troglodytes-2.1.4 (GCF_000001515.6) 1 NC_006468.3 (206057974..206084614)

Chromosome 1 - NC_006468.4Genomic Context describing neighboring genes Neighboring gene inositol-trisphosphate 3-kinase B Neighboring gene 40S ribosomal protein S27-like Neighboring gene uncharacterized LOC107970393 Neighboring gene uncharacterized LOC104004760 Neighboring gene uncharacterized LOC107974248

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Alzheimer's disease, organism-specific biosystem (from KEGG)
    Alzheimer's disease, organism-specific biosystemAlzheimer's disease (AD) is a chronic disorder that slowly destroys neurons and causes serious cognitive disability. AD is associated with senile plaques and neurofibrillary tangles (NFTs). Amyloid-b...
  • Alzheimer's disease, conserved biosystem (from KEGG)
    Alzheimer's disease, conserved biosystemAlzheimer's disease (AD) is a chronic disorder that slowly destroys neurons and causes serious cognitive disability. AD is associated with senile plaques and neurofibrillary tangles (NFTs). Amyloid-b...
  • Delta-Notch Signaling Pathway, organism-specific biosystem (from WikiPathways)
    Delta-Notch Signaling Pathway, organism-specific biosystemThere are 4 Notch receptors in humans (Notch 1-4) that bind to a family of 5 ligands (Jagged 1 and 2 and Delta-like 1-3). The Notch receptors are expressed on the cell surface as heterodimeric protei...
  • Neurotrophin signaling pathway, organism-specific biosystem (from KEGG)
    Neurotrophin signaling pathway, organism-specific biosystemNeurotrophins are a family of trophic factors involved in differentiation and survival of neural cells. The neurotrophin family consists of nerve growth factor (NGF), brain derived neurotrophic facto...
  • Neurotrophin signaling pathway, conserved biosystem (from KEGG)
    Neurotrophin signaling pathway, conserved biosystemNeurotrophins are a family of trophic factors involved in differentiation and survival of neural cells. The neurotrophin family consists of nerve growth factor (NGF), brain derived neurotrophic facto...
  • Notch Signaling Pathway, organism-specific biosystem (from WikiPathways)
    Notch Signaling Pathway, organism-specific biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
  • Notch signaling, organism-specific biosystem (from KEGG)
    Notch signaling, organism-specific biosystemFunctional set; Cellular processes; Cell signaling
  • Notch signaling, conserved biosystem (from KEGG)
    Notch signaling, conserved biosystemFunctional set; Cellular processes; Cell signaling
  • Notch signaling pathway, organism-specific biosystem (from KEGG)
    Notch signaling pathway, organism-specific biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
  • Notch signaling pathway, conserved biosystem (from KEGG)
    Notch signaling pathway, conserved biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...

Markers

Homology

Preferred Names
presenilin-2
Names
presenilin 2 (Alzheimer disease 4)
XP_001142009.2
XP_009439853.1
XP_009439855.1
XP_009439856.1
XP_016795400.1
XP_016795418.1
XP_016795421.1

RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pan_tro 3.0 Primary Assembly

Genomic

  1. NC_006468.4 Reference Pan_tro 3.0 Primary Assembly

    Range
    205919664..205945445
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016939911.1XP_016795400.1  presenilin-2 isoform X1

    UniProtKB/TrEMBL
    H2R821
    Conserved Domains (1) summary
    pfam01080
    Location:82438
    Presenilin; Presenilin
  2. XM_016939929.1XP_016795418.1  presenilin-2 isoform X3

  3. XM_016939932.1XP_016795421.1  presenilin-2 isoform X4

  4. XM_001142009.5XP_001142009.2  presenilin-2 isoform X1

    See identical proteins and their annotated locations for XP_001142009.2

    UniProtKB/TrEMBL
    H2R821
    Conserved Domains (1) summary
    pfam01080
    Location:82438
    Presenilin; Presenilin
  5. XM_009441580.2XP_009439855.1  presenilin-2 isoform X2

    See identical proteins and their annotated locations for XP_009439855.1

    Conserved Domains (1) summary
    pfam01080
    Location:82437
    Presenilin; Presenilin
  6. XM_009441578.2XP_009439853.1  presenilin-2 isoform X1

    See identical proteins and their annotated locations for XP_009439853.1

    UniProtKB/TrEMBL
    H2R821
    Conserved Domains (1) summary
    pfam01080
    Location:82438
    Presenilin; Presenilin
  7. XM_009441581.2XP_009439856.1  presenilin-2 isoform X5

    Conserved Domains (1) summary
    pfam01080
    Location:1349
    Presenilin; Presenilin
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