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DVL1 dishevelled segment polarity protein 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 457191, updated on 2-Nov-2023

Summary

Official Symbol
DVL1provided by VGNC
Official Full Name
dishevelled segment polarity protein 1provided by VGNC
Primary source
VGNC:VGNC:10606
Locus tag
CK820_G0053710
See related
Ensembl:ENSPTRG00000000025
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
DSH; DVL-1
Orthologs
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Genomic context

See DVL1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_04 current NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (663215..677418, complement)

Chromosome 1 - NC_072398.1Genomic Context describing neighboring genes Neighboring gene ceramide-1-phosphate transfer protein Neighboring gene taste 1 receptor member 3 Neighboring gene matrix remodeling associated 8 Neighboring gene aurora kinase A interacting protein 1

Genomic regions, transcripts, and products

Genomic Sequence:
NC_072398.1 Chromosome 1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables frizzled binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
segment polarity protein dishevelled homolog DVL-1
Names
DSH homolog 1
dishevelled-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012430.1NP_001012432.1  segment polarity protein dishevelled homolog DVL-1

    See identical proteins and their annotated locations for NP_001012432.1

    Status: PROVISIONAL

    Source sequence(s)
    AY665280
    UniProtKB/Swiss-Prot
    Q5IS48
    UniProtKB/TrEMBL
    A0A2J8IRR3, A0A663DEY2, K7ANK8, K7CTR2
    Related
    ENSPTRP00000055553.3, ENSPTRT00000064008.3
    Conserved Domains (5) summary
    smart00021
    Location:185
    DAX; Domain present in Dishevelled and axin
    cd04438
    Location:392474
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam00595
    Location:251336
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam02377
    Location:90247
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:478660
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

  1. NC_072398.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

    Range
    663215..677418 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016958290.3XP_016813779.1  segment polarity protein dishevelled homolog DVL-1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8IRS3, K7CTR2
    Conserved Domains (5) summary
    smart00021
    Location:185
    DAX; Domain present in Dishevelled and axin
    cd04438
    Location:417499
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam00595
    Location:251336
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam02377
    Location:90247
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:503685
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
  2. XM_016958250.2XP_016813739.1  segment polarity protein dishevelled homolog DVL-1 isoform X2

    UniProtKB/TrEMBL
    K7CTR2
    Conserved Domains (5) summary
    smart00021
    Location:185
    DAX; Domain present in Dishevelled and axin
    cd04438
    Location:417499
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam00595
    Location:251336
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam02377
    Location:90247
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:503571
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal