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NR1H2 nuclear receptor subfamily 1 group H member 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 456227, updated on 3-Dec-2024

Summary

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Official Symbol
NR1H2provided by VGNC
Official Full Name
nuclear receptor subfamily 1 group H member 2provided by VGNC
Primary source
VGNC:VGNC:3627
Locus tag
CK820_G0051530
See related
Ensembl:ENSPTRG00000011337
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See NR1H2 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 20 NC_072418.2 (53264648..53271311)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 19 NC_072417.1 (53264674..53271375)

Chromosome 20 - NC_072418.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104003412 Neighboring gene napsin-A-like Neighboring gene napsin A aspartic peptidase Neighboring gene DNA polymerase delta 1, catalytic subunit Neighboring gene Spi-B transcription factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
oxysterols receptor LXR-beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072418.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    53264648..53271311
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054672652.2 → XP_054528627.1  oxysterols receptor LXR-beta

    UniProtKB/TrEMBL
    A0A2J8J176, A0A2J8J180, A0A6D2Y0D4, H2QGX6, K7BSQ5

  2. XM_016936650.3 → XP_016792139.1  oxysterols receptor LXR-beta

    UniProtKB/TrEMBL
    A0A2J8J176, A0A2J8J180, A0A6D2Y0D4, H2QGX6, K7BSQ5
    Related
    ENSPTRP00000019472.3
    Conserved Domains (2) summary
    cd06954
    Location:224 → 459
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cl02596
    Location:67 → 163
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
Nucleotide Protein
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Research Materials