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KEAP1 kelch like ECH associated protein 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 455706, updated on 29-Mar-2024

Summary

Official Symbol
KEAP1provided by VGNC
Official Full Name
kelch like ECH associated protein 1provided by VGNC
Primary source
VGNC:VGNC:6634
Locus tag
CK820_G0026525
See related
Ensembl:ENSPTRG00000010473
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 19
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 20 NC_072418.2 (13212420..13230036, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 19 NC_072417.1 (13212463..13229884, complement)

Chromosome 20 - NC_072418.2Genomic Context describing neighboring genes Neighboring gene cell division cycle 37, HSP90 cochaperone Neighboring gene microRNA mir-1181 Neighboring gene phosphodiesterase 4A Neighboring gene sphingosine-1-phosphate receptor 5 Neighboring gene U7 small nuclear RNA Neighboring gene autophagy related 4D cysteine peptidase

Genomic regions, transcripts, and products

General protein information

Preferred Names
kelch-like ECH-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001279961.1NP_001266890.1  kelch-like ECH-associated protein 1

    See identical proteins and their annotated locations for NP_001266890.1

    Status: PROVISIONAL

    Source sequence(s)
    AK305450
    UniProtKB/TrEMBL
    G2HFD6
    Related
    ENSPTRP00000017850.4, ENSPTRT00000019286.5
    Conserved Domains (5) summary
    smart00612
    Location:471517
    Kelch; Kelch domain
    PHA03098
    Location:95596
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:460503
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:67176
    BTB; BTB/POZ domain
    pfam07707
    Location:184286
    BACK; BTB And C-terminal Kelch

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072418.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    13212420..13230036 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054672418.2XP_054528393.1  kelch-like ECH-associated protein 1 isoform X2

  2. XM_009434583.5XP_009432858.1  kelch-like ECH-associated protein 1 isoform X1

    See identical proteins and their annotated locations for XP_009432858.1

    UniProtKB/TrEMBL
    A0A2J8LWE1, A0A6D2X5C6, H2QFB9
    Conserved Domains (3) summary
    PHA03098
    Location:95596
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:460503
    Kelch; KELCH repeat [structural motif]
    cd18248
    Location:56180
    BTB_POZ_KLHL19_KEAP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like ECH-associated protein 1 (KEAP1)
  3. XM_009434584.5XP_009432859.1  kelch-like ECH-associated protein 1 isoform X1

    See identical proteins and their annotated locations for XP_009432859.1

    UniProtKB/TrEMBL
    A0A2J8LWE1, A0A6D2X5C6, H2QFB9
    Conserved Domains (3) summary
    PHA03098
    Location:95596
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:460503
    Kelch; KELCH repeat [structural motif]
    cd18248
    Location:56180
    BTB_POZ_KLHL19_KEAP1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like ECH-associated protein 1 (KEAP1)
  4. XM_063800205.1XP_063656275.1  kelch-like ECH-associated protein 1 isoform X2

  5. XM_009434585.5XP_009432860.1  kelch-like ECH-associated protein 1 isoform X2

    See identical proteins and their annotated locations for XP_009432860.1

    Conserved Domains (5) summary
    smart00612
    Location:424469
    Kelch; Kelch domain
    smart00225
    Location:78179
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00038
    Location:362409
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:67176
    BTB; BTB/POZ domain
    pfam07707
    Location:184286
    BACK; BTB And C-terminal Kelch
  6. XM_054672417.2XP_054528392.1  kelch-like ECH-associated protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A2J8LWE1, A0A6D2X5C6, H2QFB9