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BECN1 beclin 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 454700, updated on 5-Oct-2018

Summary

Official Symbol
BECN1provided by VGNC
Official Full Name
beclin 1provided by VGNC
Primary source
VGNC:VGNC:9222
Locus tag
CK820_G0038950
See related
Ensembl:ENSPTRG00000022819 Ensembl:ENSPTRG00000045185
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
beclin-1
Orthologs

Genomic context

See BECN1 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
12
Annotation release Status Assembly Chr Location
105 current Clint_PTRv2 (GCF_002880755.1) 17 NC_036896.1 (13965322..13979514)
103 previous assembly Pan_troglodytes-2.1.4 (GCF_000001515.6) 17 NC_006484.3 (14559333..14573738)

Chromosome 17 - NC_036896.1Genomic Context describing neighboring genes Neighboring gene amine oxidase, copper containing 2 Neighboring gene proteasome activator subunit 3 Neighboring gene cyclin N-terminal domain containing 1 Neighboring gene cytochrome c oxidase assembly factor 3 Neighboring gene WNK lysine deficient protein kinase 4

Genomic regions, transcripts, and products

Expression

  • Project title: Tissue-specific RNA-sequencing for ten non-human primate species
  • Description: Total RNA sequencing of fifteen different tissues for ten non-human primates
  • BioProject: PRJNA271912
  • Publication: PMID 25392405
  • Analysis date: Tue Apr 3 07:13:10 2018

Pathways from BioSystems

  • Apelin signaling pathway, organism-specific biosystem (from KEGG)
    Apelin signaling pathway, organism-specific biosystemApelin is an endogenous peptide capable of binding the apelin receptor (APJ), which was originally described as an orphan G-protein-coupled receptor. Apelin and APJ are widely expressed in various ti...
  • Apoptosis - multiple species, organism-specific biosystem (from KEGG)
    Apoptosis - multiple species, organism-specific biosystemApoptosis is an evolutionarily conserved process used by multicellular organisms to developmentally regulate cell number or to eliminate cells that are potentially detrimental to the organism. The ma...
  • Apoptosis - multiple species, conserved biosystem (from KEGG)
    Apoptosis - multiple species, conserved biosystemApoptosis is an evolutionarily conserved process used by multicellular organisms to developmentally regulate cell number or to eliminate cells that are potentially detrimental to the organism. The ma...
  • Autophagy - animal, organism-specific biosystem (from KEGG)
    Autophagy - animal, organism-specific biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
  • Autophagy - animal, conserved biosystem (from KEGG)
    Autophagy - animal, conserved biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
  • Autophagy - other, organism-specific biosystem (from KEGG)
    Autophagy - other, organism-specific biosystemAutophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either ...
  • Autophagy - other, conserved biosystem (from KEGG)
    Autophagy - other, conserved biosystemAutophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either ...
  • Mitophagy - animal, organism-specific biosystem (from KEGG)
    Mitophagy - animal, organism-specific biosystemMitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to grow and function normally. However, deleterious byproducts of oxidative phosphorylation process calle...
  • Mitophagy - animal, conserved biosystem (from KEGG)
    Mitophagy - animal, conserved biosystemMitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to grow and function normally. However, deleterious byproducts of oxidative phosphorylation process calle...

General gene information

Markers

Homology

General protein information

Preferred Names
Beclin-1; beclin-1
Names
beclin 1 (coiled-coil, myosin-like BCL2 interacting protein)
beclin 1, autophagy related

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Clint_PTRv2 Primary Assembly

Genomic

  1. NC_036896.1 Reference Clint_PTRv2 Primary Assembly

    Range
    13965322..13979514
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_511522.7XP_511522.2  beclin-1 isoform X1

    See identical proteins and their annotated locations for XP_511522.2

    UniProtKB/TrEMBL
    H2R446
    Related
    ENSPTRP00000078128.1
    Conserved Domains (2) summary
    pfam15285
    Location:107129
    BH3; Beclin-1 BH3 domain, Bcl-2-interacting
    pfam04111
    Location:135445
    APG6; Autophagy protein Apg6
  2. XM_003953012.4XP_003953061.1  beclin-1 isoform X1

    See identical proteins and their annotated locations for XP_003953061.1

    UniProtKB/TrEMBL
    H2R446
    Related
    ENSPTRP00000046569.3
    Conserved Domains (2) summary
    pfam15285
    Location:107129
    BH3; Beclin-1 BH3 domain, Bcl-2-interacting
    pfam04111
    Location:135445
    APG6; Autophagy protein Apg6
  3. XM_009432134.3XP_009430409.1  beclin-1 isoform X4

    See identical proteins and their annotated locations for XP_009430409.1

    Related
    ENSPTRP00000059855.2
    Conserved Domains (3) summary
    pfam04111
    Location:135348
    APG6; Autophagy protein Apg6
    pfam12777
    Location:196269
    MT; Microtubule-binding stalk of dynein motor
    pfam15285
    Location:107129
    BH3; Beclin-1 BH3 domain, Bcl-2-interacting
  4. XM_009432132.3XP_009430407.1  beclin-1 isoform X2

    Conserved Domains (3) summary
    pfam04111
    Location:135327
    APG6; Autophagy protein Apg6
    pfam12777
    Location:196269
    MT; Microtubule-binding stalk of dynein motor
    pfam15285
    Location:107129
    BH3; Beclin-1 BH3 domain, Bcl-2-interacting
  5. XM_009432133.3XP_009430408.1  beclin-1 isoform X3

    See identical proteins and their annotated locations for XP_009430408.1

    Conserved Domains (3) summary
    pfam04111
    Location:135378
    APG6; Autophagy protein Apg6
    pfam12777
    Location:196269
    MT; Microtubule-binding stalk of dynein motor
    pfam15285
    Location:107129
    BH3; Beclin-1 BH3 domain, Bcl-2-interacting
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