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MED1 mediator complex subunit 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 454629, updated on 5-Oct-2018

Summary

Official Symbol
MED1provided by VGNC
Official Full Name
mediator complex subunit 1provided by VGNC
Primary source
VGNC:VGNC:9369
Locus tag
CK820_G0039169
See related
Ensembl:ENSPTRG00000009091
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
PPARBP
Orthologs

Genomic context

See MED1 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
17
Annotation release Status Assembly Chr Location
105 current Clint_PTRv2 (GCF_002880755.1) 17 NC_036896.1 (17297696..17344609)
103 previous assembly Pan_troglodytes-2.1.4 (GCF_000001515.6) 17 NC_006484.3 (17940451..17988182)

Chromosome 17 - NC_036896.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene cyclin dependent kinase 12 Neighboring gene U6 spliceosomal RNA Neighboring gene F-box and leucine rich repeat protein 20 Neighboring gene transcription factor CP2-like protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Tissue-specific RNA-sequencing for ten non-human primate species
  • Description: Total RNA sequencing of fifteen different tissues for ten non-human primates
  • BioProject: PRJNA271912
  • Publication: PMID 25392405
  • Analysis date: Tue Apr 3 07:13:10 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Endocrine resistance, organism-specific biosystem (from KEGG)
    Endocrine resistance, organism-specific biosystemEndocrine therapy is a key treatment strategy to control or eradicate hormone-responsive breast cancer. The most commonly used endocrine therapy agents are selective estrogen receptor modulators (SER...
  • Endocrine resistance, conserved biosystem (from KEGG)
    Endocrine resistance, conserved biosystemEndocrine therapy is a key treatment strategy to control or eradicate hormone-responsive breast cancer. The most commonly used endocrine therapy agents are selective estrogen receptor modulators (SER...
  • Thyroid hormone signaling pathway, organism-specific biosystem (from KEGG)
    Thyroid hormone signaling pathway, organism-specific biosystemThe thyroid hormones (THs) are important regulators of growth, development and metabolism. The action of TH is mainly mediated by T3 (3,5,3'-triiodo-L-thyronine). Thyroid hormones, L-thyroxine (T4) a...

General gene information

Markers

Homology

General protein information

Preferred Names
mediator of RNA polymerase II transcription subunit 1
Names
PPAR binding protein
peroxisome proliferator-activated receptor binding protein

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Clint_PTRv2 Primary Assembly

Genomic

  1. NC_036896.1 Reference Clint_PTRv2 Primary Assembly

    Range
    17297696..17344609
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016930773.2XP_016786262.1  mediator of RNA polymerase II transcription subunit 1 isoform X2

  2. XM_016930776.2XP_016786265.1  mediator of RNA polymerase II transcription subunit 1 isoform X4

  3. XM_016930777.2XP_016786266.1  mediator of RNA polymerase II transcription subunit 1 isoform X4

  4. XM_001172406.6XP_001172406.1  mediator of RNA polymerase II transcription subunit 1 isoform X1

    See identical proteins and their annotated locations for XP_001172406.1

    UniProtKB/TrEMBL
    H2QCU3
    Related
    ENSPTRP00000015490.5
    Conserved Domains (2) summary
    pfam10744
    Location:60426
    Med1; Mediator of RNA polymerase II transcription subunit 1
    cl25751
    Location:9421079
    DUF4045; Domain of unknown function (DUF4045)
  5. XM_016930774.2XP_016786263.1  mediator of RNA polymerase II transcription subunit 1 isoform X2

  6. XM_016930775.2XP_016786264.1  mediator of RNA polymerase II transcription subunit 1 isoform X3

    Conserved Domains (2) summary
    pfam04637
    Location:816880
    Herpes_pp85; Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25)
    pfam10744
    Location:1254
    Med1; Mediator of RNA polymerase II transcription subunit 1
  7. XM_016930778.2XP_016786267.1  mediator of RNA polymerase II transcription subunit 1 isoform X5

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