POLR2A RNA polymerase II subunit A [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: POLR2Aprovided by VGNC
Official Full Name: RNA polymerase II subunit Aprovided by VGNC
Primary source: VGNC:VGNC:48945
Locus tag: CK820_G0036797
See related: Ensembl:ENSPTRG00000008691
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 30

Annotation release	Status	Assembly	Chr	Location
RS_2023_04	current	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	17	NC_072415.1 (16236387..16266762)

Chromosome 17 - NC_072415.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_072415.1 Chromosome 17 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH80168 (e-PCR)
- UniSTS:91921

WI-1288 (e-PCR)
- UniSTS:39990

WI-16243 (e-PCR)
- UniSTS:7743

G43606 (e-PCR)
- UniSTS:95041

RH104382 (e-PCR)
- UniSTS:98707

Homology

Homologs of the POLR2A gene: The POLR2A gene is conserved in human, Rhesus monkey, dog, cow, mouse, rat, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
Orthologs from Annotation Pipeline: 431 organisms have orthologs with human gene POLR2A
Orthologs

General protein information

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Preferred Names: DNA-directed RNA polymerase II subunit RPB1

Names: polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A

XP_016786944.1

EC 2.7.7.48

EC 2.7.7.6

XP_024205979.1

EC 2.7.7.48

EC 2.7.7.6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

NC_072415.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Range

16236387..16266762

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016931455.3 → XP_016786944.1 DNA-directed RNA polymerase II subunit RPB1 isoform X1

Related

ENSPTRP00000067657.1

Conserved Domains (5) summary

cd02584
Location:1058 → 1476

RNAP_II_Rpb1_C; Largest subunit (Rpb1) of Eukaryotic RNA polymerase II (RNAP II), C-terminal domain

smart01104
Location:1491 → 1610

CTD; Spt5 C-terminal nonapeptide repeat binding Spt4

cd02733
Location:19 → 876

RNAP_II_RPB1_N; Largest subunit (Rpb1) of eukaryotic RNA polymerase II (RNAP II), N-terminal domain

pfam05109
Location:1854 → 1959

Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

pfam04992
Location:896 → 1079

RNA_pol_Rpb1_6; RNA polymerase Rpb1, domain 6
XM_024350211.2 → XP_024205979.1 DNA-directed RNA polymerase II subunit RPB1 isoform X2

Conserved Domains (5) summary

cd02584
Location:1025 → 1443

RNAP_II_Rpb1_C; Largest subunit (Rpb1) of Eukaryotic RNA polymerase II (RNAP II), C-terminal domain

smart01104
Location:1458 → 1577

CTD; Spt5 C-terminal nonapeptide repeat binding Spt4

cd02733
Location:1 → 843

RNAP_II_RPB1_N; Largest subunit (Rpb1) of eukaryotic RNA polymerase II (RNAP II), N-terminal domain

pfam05109
Location:1821 → 1926

Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

pfam04992
Location:863 → 1046

RNA_pol_Rpb1_6; RNA polymerase Rpb1, domain 6