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BCAR1 BCAR1 scaffold protein, Cas family member [ Pan troglodytes (chimpanzee) ]

Gene ID: 454246, updated on 10-Oct-2024

Summary

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Official Symbol
BCAR1provided by VGNC
Official Full Name
BCAR1 scaffold protein, Cas family memberprovided by VGNC
Primary source
VGNC:VGNC:10129
Locus tag
CK820_G0042729
See related
Ensembl:ENSPTRG00000008357
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See BCAR1 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 18 NC_072416.2 (73338543..73378435, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 16 NC_072414.1 (73338449..73378341, complement)

Chromosome 18 - NC_072416.2Genomic Context describing neighboring genes Neighboring gene chymotrypsinogen B Neighboring gene chymotrypsinogen B2 Neighboring gene uncharacterized LOC129137355 Neighboring gene U6 spliceosomal RNA Neighboring gene craniofacial development protein 1 Neighboring gene small nucleolar RNA SNORA76

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
breast cancer anti-estrogen resistance protein 1
Names
BCAR1, Cas family scaffold protein
BCAR1, Cas family scaffolding protein
breast cancer anti-estrogen resistance 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072416.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    73338543..73378435 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024349954.2 → XP_024205722.1  breast cancer anti-estrogen resistance protein 1 isoform X17

    UniProtKB/TrEMBL
    A0A2I3SDR4, A0A2I3T4J5, A0A2J8Q698, A0A6D2XZM7
    Conserved Domains (4) summary
    cd11552
    Location:472 → 628
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:23 → 89
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    PHA03247
    Location:109 → 501
    PHA03247; large tegument protein UL36; Provisional
    pfam12026
    Location:672 → 882
    DUF3513; Domain of unknown function (DUF3513)

  2. XM_016930183.3 → XP_016785672.1  breast cancer anti-estrogen resistance protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A2I3SMA5, A0A2I3T4J5, A0A2J8Q6A1, A0A6D2W653
    Related
    ENSPTRP00000078105.1
    Conserved Domains (4) summary
    cd11552
    Location:472 → 628
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:23 → 89
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    PHA03247
    Location:109 → 501
    PHA03247; large tegument protein UL36; Provisional
    pfam12026
    Location:672 → 882
    DUF3513; Domain of unknown function (DUF3513)

  3. XM_016930182.3 → XP_016785671.1  breast cancer anti-estrogen resistance protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A2I3T4J5
    Conserved Domains (4) summary
    cd11552
    Location:490 → 646
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:23 → 89
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    PHA03247
    Location:109 → 519
    PHA03247; large tegument protein UL36; Provisional
    pfam12026
    Location:690 → 900
    DUF3513; Domain of unknown function (DUF3513)

  4. XM_016930187.3 → XP_016785676.1  breast cancer anti-estrogen resistance protein 1 isoform X9

    UniProtKB/TrEMBL
    A0A2I3T4J5, A0A2J8Q6B0, A0A6D2XKL2, H2RDY8, K7BCA2
    Related
    ENSPTRP00000059565.3
    Conserved Domains (4) summary
    cd11552
    Location:454 → 610
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd11569
    Location:735 → 867
    FAT-like_BCAR1_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:5 → 71
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    cl26464
    Location:91 → 483
    Atrophin-1; Atrophin-1 family

  5. XM_016930184.4 → XP_016785673.1  breast cancer anti-estrogen resistance protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A2I3T4J5
    Conserved Domains (3) summary
    cd11552
    Location:472 → 628
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:5 → 71
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    pfam12026
    Location:673 → 882
    DUF3513; Domain of unknown function (DUF3513)

  6. XM_016930185.4 → XP_016785674.1  breast cancer anti-estrogen resistance protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A2I3T4J5
    Conserved Domains (4) summary
    cd11552
    Location:472 → 628
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd11569
    Location:753 → 885
    FAT-like_BCAR1_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:5 → 71
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    cl26464
    Location:91 → 501
    Atrophin-1; Atrophin-1 family

  7. XM_063797438.1 → XP_063653508.1  breast cancer anti-estrogen resistance protein 1 isoform X10

  8. XM_016930181.4 → XP_016785670.1  breast cancer anti-estrogen resistance protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A2I3RA83

  9. XM_016930191.4 → XP_016785680.1  breast cancer anti-estrogen resistance protein 1 isoform X16

    UniProtKB/TrEMBL
    A0A2I3SRL3, A0A2I3T4J5, A0A2J8Q6A5, A0A6D2WR36
    Related
    ENSPTRP00000079661.1
    Conserved Domains (4) summary
    cd11552
    Location:500 → 656
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd11569
    Location:781 → 913
    FAT-like_BCAR1_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:51 → 117
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    cl26464
    Location:137 → 529
    Atrophin-1; Atrophin-1 family

  10. XM_054668468.2 → XP_054524443.1  breast cancer anti-estrogen resistance protein 1 isoform X10

  11. XM_016930190.3 → XP_016785679.1  breast cancer anti-estrogen resistance protein 1 isoform X13

    UniProtKB/TrEMBL
    A0A2I3RA83

  12. XM_016930179.3 → XP_016785668.1  breast cancer anti-estrogen resistance protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3RA83, A0A2I3SNJ7, A0A2J8Q6A7, A0A6D2VTA6
    Related
    ENSPTRP00000078096.1
    Conserved Domains (4) summary
    cd11552
    Location:472 → 628
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:4 → 71
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    PHA03247
    Location:91 → 501
    PHA03247; large tegument protein UL36; Provisional
    pfam12026
    Location:672 → 882
    DUF3513; Domain of unknown function (DUF3513)

  13. XM_016930180.4 → XP_016785669.1  breast cancer anti-estrogen resistance protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3RA83, A0A2J8Q6A9, A0A803KLP0, K7D5G9
    Conserved Domains (4) summary
    cd11552
    Location:454 → 610
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:4 → 71
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    PHA03247
    Location:91 → 483
    PHA03247; large tegument protein UL36; Provisional
    pfam12026
    Location:654 → 864
    DUF3513; Domain of unknown function (DUF3513)

  14. XM_054668470.1 → XP_054524445.1  breast cancer anti-estrogen resistance protein 1 isoform X14

    UniProtKB/TrEMBL
    A0A2J8Q6B1

  15. XM_054668469.1 → XP_054524444.1  breast cancer anti-estrogen resistance protein 1 isoform X12

  16. XM_016930189.3 → XP_016785678.1  breast cancer anti-estrogen resistance protein 1 isoform X12

    UniProtKB/TrEMBL
    A0A2I3T4J5
    Conserved Domains (3) summary
    cd11552
    Location:443 → 599
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    pfam12026
    Location:644 → 853
    DUF3513; Domain of unknown function (DUF3513)
    cl17036
    Location:1 → 41
    SH3; Src Homology 3 domain superfamily

  17. XM_063797440.1 → XP_063653510.1  breast cancer anti-estrogen resistance protein 1 isoform X15

  18. XM_016930186.4 → XP_016785675.1  breast cancer anti-estrogen resistance protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A2I3T4J5
    Conserved Domains (4) summary
    cd11552
    Location:470 → 626
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:3 → 69
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    PHA03247
    Location:89 → 499
    PHA03247; large tegument protein UL36; Provisional
    pfam12026
    Location:670 → 880
    DUF3513; Domain of unknown function (DUF3513)

  19. XM_016930188.4 → XP_016785677.1  breast cancer anti-estrogen resistance protein 1 isoform X11

    UniProtKB/TrEMBL
    A0A2I3RWP5, A0A2I3T4J5, A0A2J8Q6C3, A0A6D2WQG1
    Related
    ENSPTRP00000069143.1
    Conserved Domains (4) summary
    cd11552
    Location:452 → 608
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:3 → 69
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    PHA03247
    Location:89 → 481
    PHA03247; large tegument protein UL36; Provisional
    pfam12026
    Location:652 → 862
    DUF3513; Domain of unknown function (DUF3513)
Nucleotide Protein
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