MMP2 matrix metallopeptidase 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: MMP2provided by VGNC
Official Full Name: matrix metallopeptidase 2provided by VGNC
Primary source: VGNC:VGNC:5839
Locus tag: CK820_G0016667
See related: Ensembl:ENSPTRG00000008123
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2023_04	current	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	16	NC_072414.1 (53433593..53460627)

Chromosome 16 - NC_072414.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_072414.1 Chromosome 16 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

PMC179881P2 (e-PCR)
- UniSTS:271663

D16S2825 (e-PCR)
- UniSTS:153395

D16S2904 (e-PCR)
- UniSTS:153474

G62045 (e-PCR)
- UniSTS:139144

STS-M55593 (e-PCR)
- UniSTS:66965

WI-18839 (e-PCR)
- UniSTS:9943

RH69324 (e-PCR)
- UniSTS:30687

MMP2_210 (e-PCR)
- UniSTS:277493

Mmp2 (e-PCR), detects polymorphism
- UniSTS:495865

Homology

Homologs of the MMP2 gene: The MMP2 gene is conserved in human, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.
Orthologs from Annotation Pipeline: 505 organisms have orthologs with human gene MMP2
Orthologs

General protein information

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Preferred Names: 72 kDa type IV collagenase

Names: matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase); matrix metalloproteinase 2

XP_016785345.1

EC 3.4.24.24

XP_016785346.1

EC 3.4.24.24

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

NC_072414.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Range

53433593..53460627

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016929856.2 → XP_016785345.1 72 kDa type IV collagenase isoform X1

UniProtKB/TrEMBL

A0A2J8MWS1, A0A6D2XYB6

Related

ENSPTRP00000087749.1

Conserved Domains (4) summary

smart00059
Location:342 → 390

FN2; Fibronectin type 2 domain

cd00094
Location:466 → 660

HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...

pfam00413
Location:118 → 446

Peptidase_M10; Matrixin

pfam01471
Location:70 → 97

PG_binding_1; Putative peptidoglycan binding domain
XM_016929857.3 → XP_016785346.1 72 kDa type IV collagenase isoform X2

UniProtKB/TrEMBL

A0A2J8MWP5, A0A2R9C207, A0A6D2W0F6

Related

ENSPTRP00000013860.5

Conserved Domains (4) summary

smart00059
Location:292 → 340

FN2; Fibronectin type 2 domain

cd00094
Location:416 → 610

HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...

pfam00413
Location:68 → 396

Peptidase_M10; Matrixin

pfam01471
Location:20 → 47

PG_binding_1; Putative peptidoglycan binding domain