U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MAP2K5 mitogen-activated protein kinase kinase 5 [ Pan troglodytes (chimpanzee) ]

Gene ID: 453532, updated on 10-Jul-2025
Official Symbol
MAP2K5provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase 5provided by VGNC
Primary source
VGNC:VGNC:7530
Locus tag
CK820_G0008225
See related
EnsemblRapid:ENSPTRG00045042355
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table
See MAP2K5 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 16 NC_072414.2 (59538692..59802134)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 15 NC_072413.1 (59513550..59776989)

Chromosome 16 - NC_072414.2Genomic Context describing neighboring genes Neighboring gene IQ motif containing H Neighboring gene uncharacterized LOC104002350 Neighboring gene chromosome 15 C15orf61 homolog Neighboring gene collagen alpha-1(I) chain-like Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene uncharacterized LOC107968648 Neighboring gene SKI family transcriptional corepressor 1 Neighboring gene uncharacterized LOC134808551 Neighboring gene U6 spliceosomal RNA

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables MAP kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
dual specificity mitogen-activated protein kinase kinase 5
XP_001174812.1
XP_001174814.1

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072414.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    59538692..59802134
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001174814.6 → XP_001174814.1  dual specificity mitogen-activated protein kinase kinase 5 isoform X1

    See identical proteins and their annotated locations for XP_001174814.1

    UniProtKB/TrEMBL
    A0A2I3TKK8, A0A2J8NR01, A0A6D2WT98, H2Q9P0
    Related
    ENSPTRP00045049481.1, ENSPTRT00045082310.1
    Conserved Domains (2) summary
    cd06395
    Location:17 → 107
    PB1_Map2k5; PB1 domain is essential part of the mitogen-activated protein kinase kinase 5 (Map2k5, alias MEK5) one of the key member of the signaling kinases cascade which involved in angiogenesis and early cardiovascular development. The PB1 domain of Map2k5 ...
    cd06619
    Location:164 → 442
    PKc_MKK5; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 5

  2. XM_001174812.7 → XP_001174812.1  dual specificity mitogen-activated protein kinase kinase 5 isoform X2

    See identical proteins and their annotated locations for XP_001174812.1

    UniProtKB/TrEMBL
    A0A2I3TKK8, A0A2J8NR03, A0A6D2VX34, K7CUU8
    Related
    ENSPTRP00045049488.1, ENSPTRT00045082317.1
    Conserved Domains (2) summary
    cd06395
    Location:17 → 107
    PB1_Map2k5; PB1 domain is essential part of the mitogen-activated protein kinase kinase 5 (Map2k5, alias MEK5) one of the key member of the signaling kinases cascade which involved in angiogenesis and early cardiovascular development. The PB1 domain of Map2k5 ...
    cd06619
    Location:164 → 432
    PKc_MKK5; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 5
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials