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MT-CYB mitochondrially encoded cytochrome b [ Homo sapiens (human) ]

Gene ID: 4519, updated on 22-Sep-2022

Summary

Official Symbol
MT-CYBprovided by HGNC
Official Full Name
mitochondrially encoded cytochrome bprovided by HGNC
Primary source
HGNC:HGNC:7427
See related
MIM:516020; AllianceGenome:HGNC:7427
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MTCYB; CYTB
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in several processes, including electron transport coupled proton transport; response to cobalamin; and response to glucagon. Located in mitochondrion. Implicated in ovarian carcinoma and urinary bladder cancer. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See MT-CYB in Genome Data Viewer
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) MT (non-nuclear) NC_012920.1 (14747..15887)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) MT (non-nuclear) NC_012920.1 (14747..15887)

Chromosome MT - NC_012920.1Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase subunit 6 Neighboring gene tRNA-Glu Neighboring gene tRNA-Thr Neighboring gene tRNA-Pro

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the CYTB gene: The CYTB gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, A.thaliana, and frog.

General protein information

Preferred Names
cytochrome b
YP_003024038.1
  • TAA stop codon is completed by the addition of 3' A residues to the mRNA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_012920.1 Reference assembly

    Range
    14747..15887
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_003024038.1 cytochrome b (mitochondrion) [Homo sapiens]

    See identical proteins and their annotated locations for YP_003024038.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P00156, Q9TEH4
    UniProtKB/TrEMBL
    Q0ZFD6
    Related
    ENSP00000354554.2
    Conserved Domains (1) summary
    MTH00100
    Location:1379
    CYTB; cytochrome b; Provisional