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PAK1 p21 (RAC1) activated kinase 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 451439, updated on 2-Nov-2023

Summary

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Official Symbol
PAK1provided by VGNC
Official Full Name
p21 (RAC1) activated kinase 1provided by VGNC
Primary source
VGNC:VGNC:48940
Locus tag
CK820_G0021888
See related
Ensembl:ENSPTRG00000004101
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See PAK1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_04 current NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 11 NC_072409.1 (78431053..78584203, complement)

Chromosome 11 - NC_072409.1Genomic Context describing neighboring genes Neighboring gene glycerophosphodiester phosphodiesterase domain containing 4 Neighboring gene mitochondrial import receptor subunit TOM20 homolog Neighboring gene translation initiation factor IF-2-like Neighboring gene NADPH--cytochrome P450 reductase-like Neighboring gene uncharacterized LOC107967164

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_072409.1 Chromosome 11 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase PAK 1
Names
p21 protein (Cdc42/Rac)-activated kinase 1
p21-activated kinase 1
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
XP_016777167.1
XP_016777168.1
XP_016777170.1
XP_016777171.1
XP_016777175.1
XP_016777176.1
XP_016777177.1
XP_054518544.1
XP_054518545.1
XP_054518546.1
XP_054518547.1
XP_054518548.1
XP_054518549.1
XP_054518550.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

Genomic

  1. NC_072409.1 Reference NHGRI_mPanTro3-v1.1-hic.freeze_pri

    Range
    78431053..78584203 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054662571.1 → XP_054518546.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  2. XM_016921679.3 → XP_016777168.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6
    Conserved Domains (2) summary
    cd06654
    Location:249 → 544
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  3. XM_054662570.1 → XP_054518545.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  4. XM_016921686.3 → XP_016777175.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6
    Related
    ENSPTRP00000087796.1
    Conserved Domains (2) summary
    cd06654
    Location:249 → 544
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  5. XM_054662573.1 → XP_054518548.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  6. XM_016921681.3 → XP_016777170.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6
    Related
    ENSPTRP00000085990.1
    Conserved Domains (2) summary
    cd06654
    Location:249 → 544
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  7. XM_016921678.3 → XP_016777167.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6
    Conserved Domains (2) summary
    cd06654
    Location:249 → 544
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  8. XM_016921682.3 → XP_016777171.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6
    Conserved Domains (2) summary
    cd06654
    Location:249 → 544
    STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain

  9. XM_054662572.1 → XP_054518547.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  10. XM_054662569.1 → XP_054518544.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  11. XM_054662574.1 → XP_054518549.1  serine/threonine-protein kinase PAK 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBJ2, A0A6D2X6T7, K7DSU6

  12. XM_054662575.1 → XP_054518550.1  serine/threonine-protein kinase PAK 1 isoform X4

    UniProtKB/TrEMBL
    A0A2I3TG11

  13. XM_016921687.3 → XP_016777176.1  serine/threonine-protein kinase PAK 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3TG11
    Conserved Domains (2) summary
    pfam00786
    Location:74 → 132
    PBD; P21-Rho-binding domain
    cl21453
    Location:249 → 498
    PKc_like; Protein Kinases, catalytic domain

  14. XM_016921688.3 → XP_016777177.1  serine/threonine-protein kinase PAK 1 isoform X3

    UniProtKB/TrEMBL
    A0A2I3TG11, A0A2J8MBI2, A0A6D2XRU6, H2Q4G3
    Related
    ENSPTRP00000007058.4
    Conserved Domains (2) summary
    cd06647
    Location:262 → 517
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:74 → 128
    PBD; P21-Rho-binding domain
Nucleotide Protein
Heading Accession and Version

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